Metabolic effects of oral contraceptives

UJ Gaspard - American journal of obstetrics and gynecology, 1987 - Elsevier
Combination oral contraceptives (OCs) are probably not an independent risk factor for
cardiovascular disease but through their metabolic actions, may partly amplify the effects of …

Biology: risk factor modification by OCs and HRT lipids and lipoproteins

IF Godsland - Maturitas, 2004 - Elsevier
The many effects that the oestrogens and progestagens used in oral contraceptive (OC) and
postmenopausal hormone replacement therapies (HRTs) have on lipoprotein metabolism …

Clinical trial with 3-keto-desogestrel subdermal implants

S Diaz, M Pavez, AJ Moo-Young, CW Bardin… - Contraception, 1991 - Elsevier
The study was done to assess the clinical performance and in vivo steroid release rate of 3-
keto-desogestrel subdermal implants designed to deliver 5 different doses of the progestin …

Plasma lipids and desogestrel and ethinyl estradiol: a meta-analysis

RA Lobo, JB Skinner, JS Lippman, SJ Cirillo - Fertility and sterility, 1996 - Elsevier
Objective To review the literature to determine the magnitude of the effect of 150 μg
desogestrel-30 μg ethinyl E 2, an oral contraceptive (OC) formulation, on plasma lipid …

Twelve years of clinical experience with an oral contraceptive containing 30μg ethinyloestradiol and 150μg desogestrel

K Fotherby - Contraception, 1995 - Elsevier
The clinical experience with a combined oral contraceptive (COC) containign 150 μg
desogestrel and 30 μg ethinylestradiol is reviewed. Fourteen clinical trials have been …

Effects of two progestins with different androgenic properties on hepatic endothelial lipase and high density lipoprotein2

T Kuusi, EA Nikkilä, MJ Tikkanen, S Sipinen - Atherosclerosis, 1985 - Elsevier
Thirty postmenopausal women were randomly treated with desogestrel (DG) or
levonorgestrel (LN) 125 μg/day for 3 weeks. Desogestrel reduced the serum total and free …

Serum lipid and lipoprotein changes induced by new oral contraceptives containing ethinylestradiol plus levonorgestrel or desogestrel

UJ Gaspard, J Buret, D Gillain, MA Romus, R Lambotte - Contraception, 1985 - Elsevier
Abstract Changes in serum lipid and lipoprotein levels were evaluated in a randomized
prospective study conducted in matched healthy young women before and after 6 months' …

Effects of three types of combined OC pills on blood coagulation, fibrinolysis and platelet function

RNV Prasad, S Koh, SS Ratnam - Contraception, 1989 - Elsevier
The results of a prospective longitudinal controlled study comparing the coagulation effects
of a standard low-dose combined oral contraceptive (Microgynon 30), a desogestrel …

Effects of seven low dose combined oral contraceptives on high density lipoprotein subfractions

NVANDER VANGE, HJ Kloosterboer… - … Journal of Obstetrics …, 1987 - Wiley Online Library
The effects on lipid metabolism of seven combined oral contraceptives were investigated,
particularly the effects on high density lipoprotein (HDL) subfractions, which were separated …

Desogestrel-and levonorgestrel-containing oral contraceptives have different effects on urinary excretion of prostacyclin metabolites and serum high density …

O Ylikorkala, T Kuusi, MJ Tikkanen… - The Journal of Clinical …, 1987 - academic.oup.com
Prostacyclin synthesis is stimulated in vitro by high density lipoproteins (HDL), which
themselves are differently affected by desogestrel (DG)-and levonorgestrel (LN)-containing …