Vibrio cholerae hemagglutinin (HA)/protease: an extracellular metalloprotease with multiple pathogenic activities
JA Benitez, AJ Silva - Toxicon, 2016 - Elsevier
Vibrio cholerae of serogroup O1 and O139, the etiological agent of the diarrheal disease
cholera, expresses the extracellular Zn-dependent metalloprotease hemagglutinin …
cholera, expresses the extracellular Zn-dependent metalloprotease hemagglutinin …
Identification of a Vibrio cholerae RTX toxin gene cluster that is tightly linked to the cholera toxin prophage
W Lin, KJ Fullner, R Clayton… - Proceedings of the …, 1999 - National Acad Sciences
We identify and characterize a gene cluster in El Tor Vibrio cholerae that encodes a
cytotoxic activity for HEp-2 cells in vitro. This gene cluster contains four genes and is …
cytotoxic activity for HEp-2 cells in vitro. This gene cluster contains four genes and is …
Enteroaggregative Escherichia coli Produce Intestinal Inflammation and Growth Impairment and Cause Interleukin-8 Release from Intestinal Epithelial Cells
Enteroaggregative E. coli (EAggEC) are emerging as an important cause of persistent
diarrhea, especially in children in the developing world, yet the pathogenesis of EAggEC …
diarrhea, especially in children in the developing world, yet the pathogenesis of EAggEC …
In vivo actin cross-linking induced by Vibrio cholerae type VI secretion system is associated with intestinal inflammation
AT Ma, JJ Mekalanos - … of the National Academy of Sciences, 2010 - National Acad Sciences
Type VI secretion systems (T6SSs) have recently been recognized as potential virulence
determinants of many Gram-negative bacterial pathogens. Although mechanistic studies are …
determinants of many Gram-negative bacterial pathogens. Although mechanistic studies are …
Vibrio cholerae Interactions with the Gastrointestinal Tract: Lessons from Animal Studies
JM Ritchie, MK Waldor - Molecular Mechanisms of Bacterial Infection via …, 2009 - Springer
Vibrio cholerae is a curved Gram-negative rod that causes the diarrheal disease cholera.
One hundred and twenty five years of study of V. cholerae microbiology have made this …
One hundred and twenty five years of study of V. cholerae microbiology have made this …
Detection of RTX Toxin Gene in Vibrio cholerae by PCR
KH Chow, TK Ng, KY Yuen… - Journal of clinical …, 2001 - Am Soc Microbiol
ABSTRACT A PCR that amplifies a recently discovered Vibrio cholerae RTX (repeat in toxin)
toxin gene was developed. Among 166 clinical and environmental isolates of V. cholerae …
toxin gene was developed. Among 166 clinical and environmental isolates of V. cholerae …
Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. cholerae
MG Gutierrez, HA Saka, I Chinen… - Proceedings of the …, 2007 - National Acad Sciences
Autophagy is the unique, regulated mechanism for the degradation of organelles. This
intracellular process acts as a prosurvival pathway during cell starvation or stress and is also …
intracellular process acts as a prosurvival pathway during cell starvation or stress and is also …
Back to the future: studying cholera pathogenesis using infant rabbits
JM Ritchie, H Rui, RT Bronson, MK Waldor - MBio, 2010 - Am Soc Microbiol
Cholera is a severe diarrheal disease, caused by Vibrio cholerae, for which there has been
no reproducible, nonsurgical animal model. Here, we report that orogastric inoculation of V …
no reproducible, nonsurgical animal model. Here, we report that orogastric inoculation of V …
Hemolysin and the Multifunctional Autoprocessing RTX Toxin Are Virulence Factors during Intestinal Infection of Mice with Vibrio cholerae El Tor O1 Strains
V Olivier, GK Haines III, Y Tan… - Infection and …, 2007 - Am Soc Microbiol
The seventh cholera pandemic that started in 1961 was caused by Vibrio cholerae O1
strains of the El Tor biotype. These strains produce the pore-forming toxin hemolysin, a …
strains of the El Tor biotype. These strains produce the pore-forming toxin hemolysin, a …
Acute dehydrating disease caused by Vibrio cholerae serogroups O1 and O139 induce increases in innate cells and inflammatory mediators at the mucosal surface of …
Background and aims: The general concept is that as Vibrio cholerae is not invasive, it
mediates a non-inflammatory type of infection. This is being re-evaluated based on available …
mediates a non-inflammatory type of infection. This is being re-evaluated based on available …