A review of 3D polymeric scaffolds for bone tissue engineering: principles, fabrication techniques, immunomodulatory roles, and challenges

AG Abdelaziz, H Nageh, SM Abdo, MS Abdalla… - Bioengineering, 2023 - mdpi.com
Over the last few years, biopolymers have attracted great interest in tissue engineering and
regenerative medicine due to the great diversity of their chemical, mechanical, and physical …

Progress in self-healing hydrogels and their applications in bone tissue engineering

I Erezuma, I Lukin, M Desimone, YS Zhang… - Biomaterials …, 2023 - Elsevier
Bone tissue engineering (BTE) is constantly seeking novel treatments to address bone
injuries in all their varieties. It is necessary to find new ways to create structures that perfectly …

Facilely preparing carboxymethyl chitosan/hydroxyethyl cellulose hydrogel films for protective and sustained release of fibroblast growth factor 2 to accelerate dermal …

KT Le, CT Nguyen, TD Lac, LGT Nguyen… - Journal of Drug Delivery …, 2023 - Elsevier
Abstract Fibroblast growth factor 2 (FGF-2), a cytokine that plays a crucial role in wound
healing, has not been thoroughly applied in clinical wound treatment due to its instability …

Proteomics and transcriptomics explore the effect of mixture of herbal extract on diabetic wound healing process

Y Liu, X Zhang, L Yang, S Zhou, Y Li, Y Shen, S Lu… - Phytomedicine, 2023 - Elsevier
Background The annual incidence of diabetic foot ulcers (DFUs) has been reported to vary
from 0.2% to 11% in diabetes-specific clinical settings and less than 0.1% to 8% in …

[HTML][HTML] Programmed release of hydrogel microspheres via regulating the immune microenvironment to promotes bone repair

W Cai, X Xu, Y Jiang, K Cheng, F Liu, C Song… - Materials Today …, 2023 - Elsevier
Bone tissue repair is influenced by the synergistic interaction between acute immune
microenvironment and osteogenesis. In this study will be independently by film dispersion …

Potential effects of biomaterials on macrophage function and their signalling pathways

F Zhu, S Wang, X Zhu, C Pang, P Cui, F Yang… - Biomaterials …, 2023 - pubs.rsc.org
The use of biomaterials in biomedicine and healthcare has increased in recent years.
Macrophages are the primary immune cells that induce inflammation and tissue repair after …

Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals.

S Chen, C Chu, C Wang, Y Yang, Z Xu, Y Qu, Y Man - Biomaterials, 2024 - Elsevier
Extracellular matrix (ECM) scaffold membranes have exhibited promising potential to better
the outcomes of wound healing by creating a regenerative microenvironment around …

Heparin-mimicking polymer-based hydrogel matrix regulates macrophage polarization by controlling cell adhesion

JH Jeong, SS Hur, S Lobionda, S Chaycham… - Biochemical and …, 2023 - Elsevier
The physicochemical properties of biomaterials influence cell adhesion, shape, and
polarization of macrophages. In this study, we aimed to evaluate the polarization of …

Current multi-scale biomaterials for tissue regeneration following spinal cord injury

Y ang Zhang, Z huan Wu, J feng Wu, T dong Li… - Neurochemistry …, 2024 - Elsevier
Spinal cord injury (SCI) may cause loss of motor and sensory function, autonomic
dysfunction, and thus disrupt the quality of life of patients, leading to severe disability and …

Modern advances in spinal cord regeneration: hydrogel combined with neural stem cells

O Rybachuk, Y Nesterenko, V Zhovannyk - Frontiers in Pharmacology, 2024 - frontiersin.org
Severe spinal cord injuries (SCI) lead to loss of functional activity of the body below the
injury site, affect a person's ability to self-care and have a direct impact on performance. Due …