Multi-organ dysfunction is seen in nearly 40–60% of all patients presenting with sepsis,
including renal and cardiac dysfunction. Cardiorenal syndrome type-5 reflects concomitant …

In recent years, a number of techniques have been studied and developed in the field of
renal replacement therapy in the septic patient. Manipulation of ultrafiltrate dose, membrane …

Background. High-volume haemofiltration (HVHF) has been suggested as an adjuvant
treatment of septic shock due to its capacities to remove from blood both pro-and anti …

Evidence is accumulating showing that septic acute kidney injury (AKI) is different from non-
septic AKI. Specifically, a large body of research points to apoptotic processes underlying …

High-volume hemofiltration is an extracorporeal therapy that has been available in the
intensive care unit for more than 10 yr. Recent improvements in technology have made its …

Purpose We compared hemodynamic and biological effects of the Cascade system, which
uses very high volume hemofiltration (HVHF)(120 mL kg− 1 h− 1), with those of usual care in …

Currently the treatment mainstay of sepsis is early and appropriate antibiotic therapy,
accompanied by aggressive fluid administration, the use of vasopressors when needed and …

The treatment of sepsis is an ongoing challenge for clinicians; despite the wide choice of
effective antibiotics to treat infection, sepsis remains the leading cause of morbidity and …

Continuous blood purification technology such as hemodiafiltration has been used
worldwide for saving patients suffering from severe diseases or organ function failure …

The foremost function of the kidneys is to maintain fluid and electrolyte balance, by a tightly
controlled system that is able to maintain homeostasis even in perilous metabolic situations …