Next generation prophylactic human papillomavirus vaccines

JT Schiller, M Müller - The lancet oncology, 2015 - thelancet.com
The two licensed bivalent and quadrivalent human papillomavirus (HPV) L1 (the major
papillomavirus virion protein) virus-like particle (VLP) vaccines are regarded as safe …

The next generation of HPV vaccines: nonavalent vaccine V503 on the horizon

A Chatterjee - Expert review of vaccines, 2014 - Taylor & Francis
HPV infection with 'high-risk'genotypes is associated with ano-genital and oropharyngeal
cancers. Two currently licensed prophylactic HPV vaccines designed to prevent disease …

Immune responses against virus and tumor in cervical carcinogenesis: treatment strategies for avoiding the HPV-induced immune escape

P Conesa-Zamora - Gynecologic oncology, 2013 - Elsevier
Despite the availability of prophylactic vaccines against human papillomavirus (HPV),
cervical cancer (CC) is still a major problem globally. It is the cancer with the second highest …

Characterization of an Escherichia coli-derived human papillomavirus type 16 and 18 bivalent vaccine

Y Gu, M Wei, D Wang, Z Li, M Xie, H Pan, T Wu… - Vaccine, 2017 - Elsevier
Human papillomavirus (HPV) types 16 and 18 account for approximately 70% of cervical
cancer worldwide. Neutralizing HPV prophylactic vaccines offer significant benefit, as they …

Protection against human papillomavirus type 16-induced tumors in C57BL/6 mice by mucosal vaccination with Lactococcus lactis NZ9000 expressing E6 oncoprotein

S Taghinezhad-S, AH Mohseni, H Keyvani… - Microbial …, 2019 - Elsevier
Recombinant strains of Lactococcus lactis NZ9000 that express native and codon-optimized
E6 protein (fused to the SPusp45 secretion signal) were successfully constructed by using …

Targeting human papillomavirus genome replication for antiviral drug discovery

J Archambault, T Melendy - Antiviral therapy, 2013 - journals.sagepub.com
Human papillomavirus (HPV) infections are a major human health problem; they are the
cause of recurrent benign warts and of several cancers of the anogenital tract and head and …

Serum antibodies to human papillomavirus (HPV) pseudovirions correlate with natural infection for 13 genital HPV types

H Faust, MM Jelen, M Poljak, I Klavs, V Učakar… - Journal of Clinical …, 2013 - Elsevier
BACKGROUND: Serology for human papillomaviruses (HPV) types-16 and-18 is
established as an important tool for studies of HPV vaccinology and epidemiology. However …

[HTML][HTML] Small circular DNAs in human pathology

SC Barreto, M Uppalapati… - The Malaysian journal of …, 2014 - ncbi.nlm.nih.gov
In general, human pathogen-related small circular deoxyribonucleic acid (DNA) molecules
are bacterial plasmids and a group of viral genomes. Plasmids are extra-chromosomal small …

Observations on the expression of human papillomavirus major capsid protein in HeLa cells

CY Xiao, BB Fu, ZY Li, G Mushtaq, MA Kamal… - Cancer cell …, 2015 - Springer
Background The goal of this study was to identify the nature of the inclusion bodies that have
been found in HeLa cells (cervical cancer immortal cell line) by electron microscope and to …

Cervical cancer gene therapy by gene loaded PEG-PLA nanomedicine

B Liu, SM Han, XY Tang, L Han… - Asian Pacific Journal of …, 2014 - koreascience.kr
Abstract Background and Aims: Advances in the treatment of cervical cancer over the last
decade have predominantly involved the development of genes directed at molecular …