Radiation pneumonitis (RP) and radiation fibrosis (RF) are two dose-limiting toxicities of
radiotherapy (RT), especially for lung, and esophageal cancer. It occurs in 5–20% of …

The three-dimensional dose, volume, and outcome data for lung are reviewed in detail. The
rate of symptomatic pneumonitis is related to many dosimetric parameters, and there are no …

This document is the report of a task group of the AAPM and has been prepared primarily to
advise medical physicists involved in the external‐beam radiation therapy of patients with …

Purpose: To identify a clinically relevant and available parameter upon which to identify non-
small cell lung cancer (NSCLC) patients at risk for pneumonitis when treated with three …

Purpose: To determine the relation between the incidence of radiation pneumonitis and the
three-dimensional dose distribution in the lung. Methods and Materials: In five institutions …

In the era of conformal therapy and intensity-modulated therapy, there is an increased desire
to raise tumor dose to facilitate improved survival and decrease normal tissue dose to …

BACKGROUND AND PURPOSE: To perform a systematic review of the predictive ability of
various dose–volume histogram (DVH) parameters (Vdose, mean lung dose (MLD), and …

Purpose: To relate lung dose-volume histogram-based factors to symptomatic radiation
pneumonitis (RP) in patients with lung cancer undergoing 3-dimensional (3D) radiotherapy …

Although radiotherapy improves locoregional control and survival in patients with non-small-
cell lung cancer, radiation pneumonitis is a common treatment-related toxicity. Many …

The goal of radiation therapy is to reduce or eliminate tumor burden while sparing normal
tissues from long-term injury. Thoracic radiation presents a unique challenge because of the …