The emergence of Zika virus and its new clinical syndromes
TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …
threat because of its potential to generate explosive epidemics and ability to cause …
Immune response to dengue and Zika
A Elong Ngono, S Shresta - Annual review of immunology, 2018 - annualreviews.org
Flaviviruses such as dengue (DENV), yellow fever (YFV), West Nile (WNV), and Zika (ZIKV)
are human pathogens of global significance. In particular, DENV causes the most prevalent …
are human pathogens of global significance. In particular, DENV causes the most prevalent …
Pathogenesis of Zika virus infection
MI Giraldo, M Gonzalez-Orozco… - Annual Review of …, 2023 - annualreviews.org
Zika virus (ZIKV) is an emerging virus from the Flaviviridae family that is transmitted to
humans by mosquito vectors and represents an important health problem. Infections in …
humans by mosquito vectors and represents an important health problem. Infections in …
Animal models in biological and biomedical research-experimental and ethical concerns
ML Andersen, LMF Winter - Anais da Academia Brasileira de Ciências, 2017 - SciELO Brasil
Animal models have been used in experimental research to increase human knowledge
and contribute to finding solutions to biological and biomedical questions. However …
and contribute to finding solutions to biological and biomedical questions. However …
Current status of Zika virus vaccines: successes and challenges
The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …
Zika vaccine development: current status
GA Poland, IG Ovsyannikova, RB Kennedy - Mayo Clinic Proceedings, 2019 - Elsevier
Zika virus outbreaks have been explosive and unpredictable and have led to significant
adverse health effects—as well as considerable public anxiety. Significant scientific work …
adverse health effects—as well as considerable public anxiety. Significant scientific work …
Evolution of two major Zika virus lineages: implications for pathology, immune response, and vaccine development
Zika virus (ZIKV) became a public health emergency of global concern in 2015 due to its
rapid expansion from French Polynesia to Brazil, spreading quickly throughout the …
rapid expansion from French Polynesia to Brazil, spreading quickly throughout the …
Zika virus vaccine development: progress in the face of new challenges
MS Diamond, JE Ledgerwood… - Annual review of …, 2019 - annualreviews.org
Zika virus (ZIKV) emerged at a global level when it spread to the Americas and began
causing congenital malformations and microcephaly in 2015. A rapid response by …
causing congenital malformations and microcephaly in 2015. A rapid response by …
Progress and works in progress: update on flavivirus vaccine development
MH Collins, SW Metz - Clinical therapeutics, 2017 - Elsevier
Most areas of the globe are endemic for at least one flavivirus, putting billions at risk for
infection. This diverse group of viral pathogens causes a range of manifestations in humans …
infection. This diverse group of viral pathogens causes a range of manifestations in humans …
CD8+ T Cell Immune Response in Immunocompetent Mice during Zika Virus Infection
H Huang, S Li, Y Zhang, X Han, B Jia, H Liu… - Journal of …, 2017 - Am Soc Microbiol
Zika virus (ZIKV) infection causees neurologic complications, including Guillain-Barré
syndrome in adults and central nervous system (CNS) abnormalities in fetuses. We …
syndrome in adults and central nervous system (CNS) abnormalities in fetuses. We …