Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Extracellular vesicles (EVs) are well-established mediators of cell-to-cell communication.
EVs can be released by every cell type and they can be classified into three major groups …

Mesenchymal stem/stromal cells (MSCs) display a variety of therapeutically relevant effects,
such as the induction of angiogenesis, particularly under hypoxic conditions. It is generally …

Extracellular vesicles (EVs) hold great clinical value as promising diagnostic biomarkers and
therapeutic agents. This field, however, is hindered by technical challenges in the isolation …

Platelets are small anucleated blood cells primarily known for their vital hemostatic role.
Allogeneic platelet concentrates (PCs) collected from healthy donors are an essential …

Exosomes (EXOs) are natural nanoparticles of endosome origin that are secreted by a
variety of cells in the body. Exosomes have been found in bio-fluids such as urine, saliva …

With recent advances in nanotechnology and therapeutic nucleic acids (TNAs), various
nucleic acid nanoparticles (NANPs) have demonstrated great promise in diagnostics and …

Coagulation and innate immunity are linked evolutionary processes that orchestrate the host
defence against invading pathogens and injury. The complement system is integral to innate …

Mesenchymal stem cells (MSCs) have emerged as a potent therapeutic tool for the treatment
of a number of pathologies, including immune pathologies. However, unwelcome effects of …

Cancer-associated thrombosis is a leading cause of non-cancer death in cancer patients
and is comprised of both arterial and venous thromboembolism (VTE). There are multiple …