Mesenchymal stem cells (MSCs) have been proven to have superior potential to be used as
therapeutic candidates in various disorders. Nevertheless, the clinical application of these …

Osteoarthritis, as a degenerative disease, is a common problem and results in high
socioeconomic costs and rates of disability. The most commonly affected joint is the knee …

Background: Poor tendon-to-bone healing in chronic rotator cuff tears (RCTs) is related to
unsatisfactory outcomes. Exosomes derived from mesenchymal stem cells reportedly …

The host immune response effecting on biomaterials is critical to determine implant fates
and bone regeneration property. Bone marrow stem cells (BMSCs) derived exosomes …

Growth plate cartilage has limited self-repair ability, leading to poor bone bridge formation
post-injury and ultimately limb growth defects in children. The current corrective surgeries …

Background. In the past decade, mesenchymal stem cells (MSCs) have been widely used
for the treatment of osteoarthritis (OA), and noncoding RNAs in exosomes may play a major …

Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …

Hyaline cartilage plays a critical role in maintaining joint function and pain. However, the
lack of blood supply, nerves, and lymphatic vessels greatly limited the self-repair and …

Osteoarthritis (OA) is a common degenerative joint disease urgently needing effective
treatments. Bone marrow mesenchymal stromal cell-derived exosomes (Exo) are …

Osteoarthritis (OA) has generally been introduced as a degenerative disease; however, it
has recently been understood as a low-grade chronic inflammatory process that could …