Alpha-synuclein (αS) is the major constituent of Lewy bodies and a pathogenic hallmark of
all synucleinopathathies, including Parkinson's disease (PD), dementia with Lewy bodies …

Mounting evidence has highlighted the implementation of big data handling and
management in the healthcare industry to improve the clinical services. Various private and …

The way sporadic Parkinson's disease (PD) is perceived has undergone drastic changes in
recent decades. For a long time, PD was considered a brain disease characterized by motor …

Parkinson's disease (PD) is a progressive neurodegenerative disorder that is characterized
by a loss of dopaminergic neurons, leading to bradykinesia, rigidity, tremor at rest, and …

Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's disease (AD). Genetic predisposition and immune dysfunction are involved in …

Parkinson's disease (PD) is one of the most common and chronic degenerative diseases in
the central nervous system. The main pathology of PD formation is the progressive loss of …

Sex differences in diseases involving oxidative and proteolytic stress are common, including
greater ischemic heart disease, Parkinson disease and stroke in men, and greater …

Deep brain stimulation (DBS) is a surgical procedure that uses electrical neuromodulation to
target specific regions of the brain, showing potential in the treatment of neurodegenerative …

Liquid–liquid phase separation (LLPS) is an emerging phenomenon in cell physiology and
diseases. The weak multivalent interaction prerequisite for LLPS is believed to be facilitated …

The question whether life style may impair the advent or course of the disease in patients
with Parkinsonism is of great importance for patients and physicians alike. We present here …