Pulmonary fibrosis and architectural remodeling of tissues can severely disrupt lung
function, often with fatal consequences. The etiology of pulmonary fibrotic diseases is varied …

Inflammation is the body's response to insults, which include infection, trauma, and
hypersensitivity. The inflammatory response is complex and involves a variety of …

Chemokines are a family of low molecular weight proteins with an essential role in leukocyte
trafficking during both homeostasis and inflammation. The CC class of chemokines consists …

Idiopathic pulmonary fibrosis (IPF) is characterized by distorted lung architecture and loss of
respiratory function. Enhanced (myo) fibroblast activation, ECM deposition, and alveolar …

Fibrogenesis is a mechanism of wound healing and repair. However, prolonged injury
causes deregulation of normal processes and results in extensive deposition of extracellular …

Idiopathic pulmonary fibrosis (IPF) is a non-neoplastic pulmonary disease that is
characterized by the formation of scar tissue within the lungs in the absence of any known …

Inflammation affects the formation and the progression of various vitreoretinal diseases. We
performed a comprehensive analysis of inflammatory immune mediators in the vitreous …

All tissues and organs can be classified according to their ability to repair and regenerate
during adult homeostasis and after injury. Some exhibit a high rate of constant cell turnover …

Graves' disease (GD) is a common autoimmune condition. At its core, stimulatory
autoantibodies are directed at the thyroid-stimulating hormone receptor (TSHR), resulting in …

Normal tissue function requires adequate supply of oxygen through blood vessels.
Understanding how blood vessels form is a challenging objective because angiogenesis is …