Fibrosis of parenchymal organs is caused by prolonged injury, deregulation of the normal
processes of wound healing, and extensive deposition of extracellular matrix (ECM) …

Group 3 pulmonary hypertension (PH) is a common complication of chronic lung disease
(CLD), including chronic obstructive pulmonary disease (COPD), interstitial lung disease …

Background Of late, high-throughput microarray and sequencing data have been
extensively used to monitor biomarkers and biological processes related to many diseases …

Alveolar epithelial cells (AECs) participate in the pathogenesis of pulmonary fibrosis,
producing pro‐inflammatory mediators and undergoing epithelial‐to‐mesenchymal …

Vascular remodeling in idiopathic pulmonary arterial hypertension (IPAH) involves
hyperproliferative and apoptosis-resistant pulmonary artery endothelial cells. In this study …

Introduction Interstitial lung disease (ILD) is a heterogeneous group of diseases
characterized by varying degrees of lung inflammation and/or fibrosis. We investigated …

There has been ongoing controversy related to what differentiates normal lung repair and
fibrosis. For example, the current prevailing concept has been that idiopathic forms of …

Organ fibrosis, the result of exaggerated, persistent, and often irreversible accumulation of
extracellular matrix, complicates numerous diseases in all organs and tissues and has …

Idiopathic Pulmonary Fibrosis (IPF) is characterized by injury and loss of lung epithelial
cells, accumulation of fibroblasts/myofibroblasts and abnormal remodeling of the lung …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and usually fatal disease,
based on a multifaceted and incompletely understood pathogenesis. Some of the cellular …