Several members of the chemokine family play an important role in reparative fibrosis and
are involved in the pathogenesis of remodeling following myocardial infarction. Chemokines …

Cardiac fibrosis contributes significantly to the phenotype of the chronically failing heart. It is
not clear whether in this setting the fibrosis is contributed by native cardiac fibroblasts or …

Introduction 3. Ang II and inflammation 4. Ang II and chemokines 5. Ang II and inflammatory
cells 6. Ang II and imbalance of inflammatory or anti-inflammatory cytokines 7. Ang II and pro …

In most cholangiopathies, liver diseases of different etiologies in which the biliary epithelium
is the primary target in the pathogenic sequence, the central mechanism involves …

Liver fibrosis is an outcome of chronic liver injury of any etiology. It is manifested by
extensive deposition of extracellular matrix (ECM) proteins that produce a fibrous scar in the …

The pathophysiology of liver injury has attracted the interest of experimentalists and
clinicians over many centuries. With the discovery of liver‐specific pericytes–formerly called …

Rationale Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterized
by progressive scarring and matrix deposition. Recent reports highlight an autoimmune …

Idiopathic pulmonary fibrosis (IPF) is a fatal chronic interstitial lung disease (ILD) that affects
lung mechanical functions and gas exchange. IPF is caused by increased fibroblast activity …

Background Pulmonary fibrosis (PF) is a growing clinical problem with limited therapeutic
options. Human umbilical cord mesenchymal stromal cell (hucMSC) therapy is being …

Pulmonary fibrosis is characterized by destruction and remodeling of the lung due to an
accumulation of collagen and other extracellular matrix components in the tissue. This …