Viruses as co-factors for the initiation or exacerbation of lung fibrosis

KM Vannella, BB Moore - Fibrogenesis & tissue repair, 2008 - Springer
Idiopathic pulmonary fibrosis (IPF) remains exactly that. The disease originates from an
unknown cause, and little is known about the mechanisms of pathogenesis. While the …

T cells, B cells, and polarized immune response in the pathogenesis of fibrosis and systemic sclerosis

C Chizzolini - Current opinion in rheumatology, 2008 - journals.lww.com
Although immunosuppressive strategies to treat patients with systemic sclerosis and allied
conditions are largely disappointing, thus indicating a permissive rather than causative role …

Cytokine signaling converging on IL11 in ILD fibroblasts provokes aberrant epithelial differentiation signatures

MT Kastlmeier, E Gonzalez-Rodriguez… - Frontiers in …, 2023 - frontiersin.org
Introduction Interstitial lung disease (ILD) is a heterogenous group of lung disorders where
destruction and incomplete regeneration of the lung parenchyma often results in persistent …

The mechanism of ligamentum flavum hypertrophy: introducing angiogenesis as a critical link that couples mechanical stress and hypertrophy

JW Hur, BJ Kim, JH Park, JH Kim, YK Park… - …, 2015 - journals.lww.com
BACKGROUND: Biochemical alterations associated with mechanical stress have been
explored as an initiating step in the pathological progression of ligamentum flavum …

[HTML][HTML] The role of circulating mesenchymal progenitor cells, fibrocytes, in promoting pulmonary fibrosis

RM Strieter, EC Keeley, MD Burdick… - Transactions of the …, 2009 - ncbi.nlm.nih.gov
The resident fibroblast has been traditionally viewed as the primary cell involved in
promoting pulmonary fibrosis. However, contemporary findings now support the concept of a …

Immunomodulation by mesenchymal stem cells in treating human autoimmune disease-associated lung fibrosis

M Liu, X Zeng, J Wang, Z Fu, J Wang, M Liu… - Stem cell research & …, 2016 - Springer
Background Interstitial pneumonia in connective tissue diseases (CTD-IP) featuring
inflammation and fibrosis is a leading cause of death in CTD-IP patients. The related …

ERS international Congress 2023: highlights from the Basic and Translational Sciences Assembly

KD Reddy, N Bizymi, A Schweikert… - ERJ Open …, 2024 - Eur Respiratory Soc
Early career members of Assembly 3 (Basic and Translational Sciences) of the European
Respiratory Society (ERS) summarise the key messages discussed during six selected …

STAT3 and suppressor of cytokine signaling 3: potential targets in lung inflammatory responses

H Gao, PA Ward - Expert opinion on therapeutic targets, 2007 - Taylor & Francis
The expanding knowledge involving the cytokine transcription factor network has provided
new insights into the acute lung inflammatory response. There are numerous lung …

Oxidative stress and inflammation can fuel cancer

FU Vaidya, AS Chhipa, N Sagar, C Pathak - Role of oxidative stress in …, 2020 - Springer
Both oxidative stress and inflammation are interdependent cellular consequences of a
biological defense system, which can fuel cancer and other pathophysiological provenience …

Glucose transporter-1 distribution in fibrotic lung disease: association with [18F]-2-fluoro-2-deoxyglucose-PET scan uptake, inflammation, and neovascularization

S El-Chemaly, D Malide, J Yao, SD Nathan, IO Rosas… - Chest, 2013 - Elsevier
Abstract Background [18 F]-2-fluoro-2-deoxyglucose (FDG)-PET scan uptake is increased in
areas of fibrosis and honeycombing in patients with idiopathic pulmonary fibrosis (IPF) …