Ecology and genomics of Actinobacteria: new concepts for natural product discovery

DA van Bergeijk, BR Terlouw, MH Medema… - Nature Reviews …, 2020 - nature.com
Actinobacteria constitute a highly diverse bacterial phylum with an unrivalled metabolic
versatility. They produce most of the clinically used antibiotics and a plethora of other natural …

Microbial fuel cells: An overview of current technology

AJ Slate, KA Whitehead, DAC Brownson… - … and sustainable energy …, 2019 - Elsevier
Research into alternative renewable energy generation is a priority, due to the ever-
increasing concern of climate change. Microbial fuel cells (MFCs) are one potential avenue …

The hidden world within plants: ecological and evolutionary considerations for defining functioning of microbial endophytes

PR Hardoim, LS Van Overbeek, G Berg… - Microbiology and …, 2015 - Am Soc Microbiol
All plants are inhabited internally by diverse microbial communities comprising bacterial,
archaeal, fungal, and protistic taxa. These microorganisms showing endophytic lifestyles …

The evolution of genome mining in microbes–a review

N Ziemert, M Alanjary, T Weber - Natural product reports, 2016 - pubs.rsc.org
Covering: 2006 to 2016 The computational mining of genomes has become an important
part in the discovery of novel natural products as drug leads. Thousands of bacterial …

Evolution and diversity of assembly-line polyketide synthases: focus review

A Nivina, KP Yuet, J Hsu, C Khosla - Chemical reviews, 2019 - ACS Publications
Assembly-line polyketide synthases (PKSs) are among the most complex protein
machineries known in nature, responsible for the biosynthesis of numerous compounds …

Synthetic biology to access and expand nature's chemical diversity

MJ Smanski, H Zhou, J Claesen, B Shen… - Nature Reviews …, 2016 - nature.com
Bacterial genomes encode the biosynthetic potential to produce hundreds of thousands of
complex molecules with diverse applications, from medicine to agriculture and materials …

Taxonomy, physiology, and natural products of Actinobacteria

EA Barka, P Vatsa, L Sanchez… - Microbiology and …, 2016 - Am Soc Microbiol
Actinobacteria are Gram-positive bacteria with high G+ C DNA content that constitute one of
the largest bacterial phyla, and they are ubiquitously distributed in both aquatic and …

Harnessing the intracellular triacylglycerols for titer improvement of polyketides in Streptomyces

W Wang, S Li, Z Li, J Zhang, K Fan, G Tan, G Ai… - Nature …, 2020 - nature.com
Pharmaceutically important polyketides such as avermectin are mainly produced as
secondary metabolites during the stationary phase of growth of Streptomyces species in …

Regulation of antibiotic production in Actinobacteria: new perspectives from the post-genomic era

HU Van Der Heul, BL Bilyk, KJ McDowall… - Natural product …, 2018 - pubs.rsc.org
Covering: 2000 to 2018 The antimicrobial activity of many of their natural products has
brought prominence to the Streptomycetaceae, a family of Gram-positive bacteria that …

[HTML][HTML] Recent advances in understanding Streptomyces

KF Chater - F1000Research, 2016 - ncbi.nlm.nih.gov
Abstract About 2,500 papers dated 2014–2016 were recovered by searching the PubMed
database for Streptomyces, which are the richest known source of antibiotics. This review …