A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD)

J Peng, M Fan, C An, F Ni, W Huang… - Basic & clinical …, 2022 - Wiley Online Library
Cannabidiol (CBD) is an abundant non‐psychoactive phytocannabinoid in cannabis
extracts which has high affinity on a series of receptors, including Type 1 cannabinoid …

Fear generalization in humans: systematic review and implications for anxiety disorder research

S Dymond, JE Dunsmoor, B Vervliet, B Roche… - Behavior therapy, 2015 - Elsevier
Fear generalization, in which conditioned fear responses generalize or spread to related
stimuli, is a defining feature of anxiety disorders. The behavioral consequences of …

Global, regional and national burden of anxiety disorders from 1990 to 2019: results from the Global Burden of Disease Study 2019

X Yang, Y Fang, H Chen, T Zhang, X Yin… - Epidemiology and …, 2021 - cambridge.org
AimsAnxiety disorders are widespread across the world. A systematic understanding of the
disease burden, temporal trend and risk factors of anxiety disorders provides the essential …

Sensitivity to change and minimal clinically important difference of the 7-item Generalized Anxiety Disorder Questionnaire (GAD-7)

A Toussaint, P Hüsing, A Gumz, K Wingenfeld… - Journal of affective …, 2020 - Elsevier
Background Effective treatment requires regular follow-up and monitoring of symptoms. We
investigated sensitivity to change and minimal clinically important difference of the …

Longitudinal changes of anxiety and depressive symptoms during the COVID-19 pandemic in Germany: The role of pre-existing anxiety, depressive, and other mental …

A Bendau, SL Kunas, S Wyka, MB Petzold… - Journal of anxiety …, 2021 - Elsevier
Especially individuals with mental disorders might experience an escalation of
psychopathological symptoms during the COVID-19 pandemic. Therefore, we investigated …

The impact of social distancing during COVID-19: A conditional process model of negative emotions, alienation, affective disorders, and post-traumatic stress disorder

Y Zhu, L Zhang, X Zhou, C Li, D Yang - Journal of affective disorders, 2021 - Elsevier
Background The social distancing during COVID-19 is likely to cause a feeling of alienation,
which may pose a threat to the public's mental health. Our research aims to examine the …

Reproducible genetic risk loci for anxiety: results from∼ 200,000 participants in the Million Veteran Program

DF Levey, J Gelernter, R Polimanti… - American Journal of …, 2020 - Am Psychiatric Assoc
Objective: Anxiety disorders are common and often disabling. The goal of this study was to
examine the genetic architecture of anxiety disorders and anxiety symptoms, which are also …

Meta-analysis of genome-wide association studies of anxiety disorders

T Otowa, K Hek, M Lee, EM Byrne, SS Mirza… - Molecular …, 2016 - nature.com
Anxiety disorders (ADs), namely generalized AD, panic disorder and phobias, are common,
etiologically complex conditions with a partially genetic basis. Despite differing on diagnostic …

Stress, definitions, mechanisms, and effects outlined: Lessons from anxiety

G Fink - Stress: Concepts, cognition, emotion, and behavior, 2016 - Elsevier
The present volume on concepts, cognition, emotion, and behavior, is the first in this new
Handbook series. The purpose of this first chapter is to provide an outline of stress, stress …

Inducing anxiety in large language models increases exploration and bias

J Coda-Forno, K Witte, AK Jagadish, M Binz… - arXiv preprint arXiv …, 2023 - arxiv.org
Large language models are transforming research on machine learning while galvanizing
public debates. Understanding not only when these models work well and succeed but also …