[HTML][HTML] Hepatocellular carcinoma in non-cirrhotic liver: A comprehensive review

A Desai, S Sandhu, JP Lai… - World journal of hepatology, 2019 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, which in
turns accounts for the sixth most common cancer worldwide. Despite being the 6 th most …

[HTML][HTML] Updating the clinical application of blood biomarkers and their algorithms in the diagnosis and surveillance of hepatocellular carcinoma: a critical review

E Shahini, G Pasculli, AG Solimando, C Tiribelli… - International Journal of …, 2023 - mdpi.com
The most common primary liver cancer is hepatocellular carcinoma (HCC), and its mortality
rate is increasing globally. The overall 5-year survival of patients with liver cancer is …

[PDF][PDF] A multi‐analyte cell‐free DNA–based blood test for early detection of hepatocellular carcinoma

N Lin, Y Lin, J Xu, D Liu, D Li, H Meng… - Hepatology …, 2022 - Wiley Online Library
The limited performance of guideline‐recommended abdominal ultrasound and serum
alpha‐fetoprotein (AFP) highlights the urgent, unmet need for new biomarkers for more …

[HTML][HTML] Utility of combining PIVKA-II and AFP in the surveillance and monitoring of hepatocellular carcinoma in the Asia-Pacific region

BN Toan, CK Tan, I Hasan, L Setiawan… - Clinical and …, 2023 - ncbi.nlm.nih.gov
Even though the combined use of ultrasound (US) and alpha-fetoprotein (AFP) is
recommended for the surveillance of hepatocellular carcinoma (HCC), the utilization of AFP …

[PDF][PDF] Current and emerging tools for hepatocellular carcinoma surveillance

N Adeniji, R Dhanasekaran - Hepatology communications, 2021 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related mortality worldwide.
Early detection of HCC enables patients to avail curative therapies that can improve patient …

Protein kinases: The key contributors in pathogenesis and treatment of nonalcoholic fatty liver disease-derived hepatocellular carcinoma

R Liu, M Qian, YY Cui - Metabolism, 2023 - Elsevier
Protein kinases (PKs), one of the largest protein families, can be further divided into different
groups based on their substrate or structure and function. PKs are important signaling …

Evaluation of the combined application of AFP, AFP‐L3%, and DCP for hepatocellular carcinoma diagnosis: a meta‐analysis

X Wang, Y Zhang, N Yang, H He, X Tao… - BioMed research …, 2020 - Wiley Online Library
The role of α‐fetoprotein (AFP) in the surveillance and diagnosis of hepatocellular
carcinoma (HCC) has been questioned in recent years due to its low sensitivity and …

Bioluminescent RAPPID sensors for the single-step detection of soluble axl and multiplex analysis of cell surface cancer biomarkers

EA Van Aalen, SFA Wouters, D Verzijl… - Analytical …, 2022 - ACS Publications
Early diagnosis of cancer is essential for the efficacy of treatment. Our group recently
developed RAPPID, a bioluminescent immunoassay platform capable of measuring a wide …

Do combined assays of serum AFP, AFP-L3, DCP, GP73, and DKK-1 efficiently improve the clinical values of biomarkers in decision-making for hepatocellular …

YS Fang, Q Wu, HC Zhao, Y Zhou, L Ye… - Expert Review of …, 2021 - Taylor & Francis
Objectives: Serum biomarkers are valuable for clinical decision-making for patients with
hepatocellular carcinoma (HCC), among which the most promising are AFP, AFP-L3, DCP …

[HTML][HTML] Diagnostic performance of extrahepatic protein induced by vitamin k absence in the hepatocellular carcinoma: a systematic review and meta-analysis

MG Perne, AV Sitar-Tăut, TG Alexescu, L Ciumărnean… - Diagnostics, 2023 - mdpi.com
Background and Objectives: the early diagnosis of hepatocellular carcinoma (HCC) benefits
from the use of alpha-fetoprotein (AFP) together with imaging diagnosis using abdominal …