A review of systemic corticosteroid use in pregnancy and the risk of select pregnancy and birth outcomes

G Bandoli, K Palmsten, CJF Smith… - Rheumatic Disease …, 2017 - rheumatic.theclinics.com
Corticosteroids are administered in pregnancy for their immunosuppressive and
antiinflammatory effects. 1 They are used to treat symptoms of autoimmune conditions …

Glucocorticosteroids: current and future directions

PJ Barnes - British journal of pharmacology, 2011 - Wiley Online Library
Glucocorticoids are the most effective anti‐inflammatory therapy for asthma yet are relatively
ineffective in chronic obstructive pulmonary disease. Glucocorticoids suppress inflammation …

Бронхиальная астма у детей

ИИ Балаболкин, ВА Булгакова - 2015 - elibrary.ru
Бронхиальная астма—хроническое воспалительное заболевание дыхательных путей,
сопровождаемое гиперреактивностью бронхов и клинически проявляемое их …

Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition

RK Bledsoe, VG Montana, TB Stanley, CJ Delves… - Cell, 2002 - cell.com
Transcriptional regulation by the glucocorticoid receptor (GR) is mediated by hormone
binding, receptor dimerization, and coactivator recruitment. Here, we report the crystal …

Neutrophilic inflammation in severe persistent asthma

A Jatakanon, C Uasuf, W Maziak, SAM Lim… - American journal of …, 1999 - atsjournals.org
Airway inflammation in severe asthma is not well characterized but may involve neutrophils.
We have compared induced sputum profiles in patients with asthma of varying severity and …

Influence of cigarette smoking on inhaled corticosteroid treatment in mild asthma

GW Chalmers, KJ Macleod, SA Little, LJ Thomson… - Thorax, 2002 - thorax.bmj.com
Background: Although inhaled corticosteroids have an established role in the treatment of
asthma, studies have tended to concentrate on non-smokers and little is known about the …

National Athletic Trainers' Association position statement: preventing sudden death in sports

DJ Casa, KM Guskiewicz… - Journal of athletic …, 2012 - meridian.allenpress.com
Objective: To present recommendations for the prevention and screening, recognition, and
treatment of the most common conditions resulting in sudden death in organized sports …

Japanese guidelines for adult asthma 2017

M Ichinose, H Sugiura, H Nagase… - Allergology …, 2017 - jstage.jst.go.jp
abstract Adult bronchial asthma is characterized by chronic airway inflammation, and
presents clinically with variable airway narrowing (wheezes and dyspnea) and cough. Long …

Histone acetylation and deacetylation: importance in inflammatory lung diseases

PJ Barnes, IM Adcock, K Ito - European Respiratory Journal, 2005 - Eur Respiratory Soc
Inflammatory lung diseases are characterised by increased expression of multiple
inflammatory genes that are regulated by proinflammatory transcription factors, such as …

Significant variability in response to inhaled corticosteroids for persistent asthma

SJ Szefler, RJ Martin, TS King, HA Boushey… - Journal of Allergy and …, 2002 - Elsevier
Background: A clinical model is needed to compare inhaled corticosteroids (ICSs) with
respect to efficacy. Objective: The purpose of this investigation was to compare the relative …