Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a life-threatening
condition of critically-ill patients, characterized by overwhelming inflammatory responses in …

Multiple sclerosis (MS) is one of the most common neurodegenerative diseases in young
adults, with early clinical symptoms seen in the central nervous system (CNS) myelin …

The association of autoimmune diseases with particular allellic products of the class-II major
histocompatibility complex (MHCII) region implicates the presentation of the offending self …

Dendritic cells (DCs) are paramount in initiating and guiding immunity towards a state of
activation or tolerance. This bidirectional capacity of DCs sets them at the center stage for …

The aim of cancer immunotherapy is to reactivate autoimmune responses to combat cancer
cells. To stimulate the immune system, immunomodulators, such as adjuvants, cytokines …

Immune homeostasis is maintained by a precise balance between effector immune cells and
regulatory immune cells. Chronic deviations from immune homeostasis, driven by a greater …

Autoimmune disorders have risen to be among the most prevalent chronic diseases across
the globe, affecting approximately 5–7% of the population. As autoimmune diseases steadily …

Polymeric nanoparticles (NPs) composed of poly (lactic-co-glycolic acid)(PLGA) have found
success in modulating antigen (Ag)-specific T cell responses for the treatment multiple …

Intraportal allogeneic islet transplantation has been demonstrated as a potential therapy for
type 1 diabetes (T1D). The placement of islets into the liver and chronic immunosuppression …

Biomaterial carriers offer modular features to control the delivery and presentation of
vaccines and immunotherapies. This tunability is a distinct capability of biomaterials …