[HTML][HTML] Tuning surface charges of peptide nanofibers for induction of antigen-specific immune tolerance: an introductory study

CYJ Lau, N Benne, B Lou, D Ter Braake… - Journal of …, 2022 - Elsevier
Induction of antigen-specific immune tolerance has emerged as the next frontier in treating
autoimmune disorders, including atherosclerosis and graft-vs-host reactions during …

Syngeneic red blood cell–induced extracellular vesicles suppress delayed‐type hypersensitivity to self‐antigens in mice

K Nazimek, E Bustos‐Morán… - Clinical & …, 2019 - Wiley Online Library
Background At present, the role of autologous cells as antigen carriers inducing immune
tolerance is appreciated. Accordingly, intravenous administration of haptenated syngeneic …

A century later, still fighting back: antigen‐specific immunotherapies for type 1 diabetes

S Rodriguez‐Fernandez… - … and Cell Biology, 2021 - Wiley Online Library
Abstract Type 1 diabetes (T1D) is a chronic metabolic disease caused by the autoimmune
destruction of insulin‐producing β‐cells. Ever since the 1920s, the fate of patients suffering …

Optimizing PLG nanoparticle-peptide delivery platforms for transplantation tolerance using an allogeneic skin transplant model

S Shah, S Daneshmandi, KR Hughes, S Yu… - Biomaterials, 2019 - Elsevier
A robust regimen for inducing allogeneic transplantation tolerance involves pre-emptive
recipient treatment with donor splenocytes (SP) rendered apoptotic by 1-ethyl-3-(3 …

Approaches to inducing antigen‐specific immune tolerance in allergy and autoimmunity: Focus on antigen‐presenting cells and extracellular vesicles

K Nazimek, K Bryniarski - Scandinavian Journal of Immunology, 2020 - Wiley Online Library
Increasing prevalence of allergic and autoimmune diseases urges clinicians and
researchers to search for new and efficient treatments. Strategies that activate antigen …

Biomaterial-based approaches to engineering immune tolerance

AE Emerson, EM Slaby, SC Hiremath… - Biomaterials Science, 2020 - pubs.rsc.org
The development of biomaterial-based therapeutics to induce immune tolerance holds great
promise for the treatment of autoimmune diseases, allergy, and graft rejection in …

An insight into the role of liposomal therapeutics in the reversion of multiple sclerosis

N Rahiman, P Zamani, A Badiee, L Arabi… - Expert Opinion on …, 2021 - Taylor & Francis
ABSTRACT Introduction Multiple Sclerosis (MS), as an autoimmune disease, has
complicated immunopathology, which makes its management relevant to various factors …

Nanomedicine approaches against parasitic worm infections

P Li, PE Rios Coronado, XRR Longstaff… - Advanced …, 2018 - Wiley Online Library
Nanomedicine approaches have the potential to transform the battle against parasitic worm
(helminth) infections, a major global health scourge from which billions are currently …

Low-dimensional nanomaterials enabled autoimmune disease treatments: Recent advances, strategies, and future challenges

L Chai, X Fan, Y Zuo, B Zhang, G Nie, N Xie… - Coordination Chemistry …, 2021 - Elsevier
Nanomaterials are playing an advancing critical role in the prevention, diagnosis, and
treatment of today's human problems. By engineering with multi-active probes including …

LILRB4 Checkpoint for Immunotherapy: Structure, Mechanism and Disease Targets

Z Xiang, X Yin, L Wei, M Peng, Q Zhu, X Lu, J Guo… - Biomolecules, 2024 - mdpi.com
LILRB4, a myeloid inhibitory receptor belonging to the family of leukocyte immunoglobulin-
like receptors (LILRs/LIRs), plays a pivotal role in the regulation of immune tolerance …