The direct modulation of T cell responses is an emerging therapeutic strategy with the
potential to modulate undesired immune responses including, autoimmune disease, and …

Background It is known that the immune tolerance can be naturally established in the
intestine, while the mechanism by which the immune tolerance development in the intestine …

Current treatments for autoimmune diseases can only ameliorate the symptoms of the
disease and may cause immunocompromised or opportunistic diseases. Recent advances …

Current treatments for autoimmune disorders rely on non-specific immunomodulatory and
global immunosuppressive drugs, which show a variable degree of efficiency and are often …

Background Islet transplantation is a promising minimally invasive approach that dispenses
with many challenges, especially immunological complications such as instant blood …

Development of a vaccine that can elicit robust HIV specific antibody responses in the
mucosal compartments is desired for effective prevention of HIV via sexual transmission …

Background: Therapeutic treatment options for chronic autoimmune disorders such as
multiple sclerosis (MS) rely largely on the use of non-specific immunosuppressive drugs …

Autoimmune diseases are heterogeneous group of disorders that together represent an
enormous societal and medical problem. CD4+ T cells have critical roles in the initiation and …

Genetic engineering of innate and adaptive immune cells represents a potential solution to
treat numerous immune-mediated pathologies. Current immune engineering methods to …

Multiple sclerosis (MS) is a highly prevalent demyelinating disorder, presumed to be driven
by an autoimmune response toward the central nervous system (CNS) components. All …