This chapter provides an overview of the pathogenesis of the major immune-mediated
diseases, the classes of drugs being developed to treat these diseases and their MoAs. The …

The last few decades have seen rapid progress in the fields of drug delivery systems,
implantable scaffolds, and tissue engineering. Broadly referred to as biomaterials, these …

The treatment of autoimmune disorders such as multiple sclerosis (MS) so far relies largely
on the use of non-specific immunosuppressive drugs, which are not able to cure the …

Antigen-specific approaches offering novel treatment options for autoimmune diseases are
gaining interest over the years. Although antigenic targets for several autoimmune diseases …

In the past 15 years, autoimmune encephalitis has become increasingly recognised, driven
by advances in the detection of neural autoantibodies that cause these disorders. 1, 2 …

Nanoparticles (NPs) possess the exciting potential to engineer specific immune responses
during different disease states. Although NPs are typically considered for their …

I am extremely grateful to my PhD advisor and mentor Professor Lonnie Shea. His
mentorship, guidance, continuous support, and patience during these years has had a …

The human immune system has evolved to exquisitely protect against an incredible variety
of assaults. To accomplish this objective, specialized cell types defined by their form and …

Согласно существующей в настоящее время гипотезе, транскутанная сенсибилизация
является одним из ведущих механизмов формирования пищевой аллергии. Цель …

EP3980458A1 - Chimeric autoantibody receptor (caar) that binds autoantibodies targeting the
central nervous system in neurological autoimmune disease - Google Patents EP3980458A1 …