[HTML][HTML] Recent Innovations of Mesoporous Silica Nanoparticles Combined with Photodynamic Therapy for Improving Cancer Treatment

DS Nady, A Hassan, MU Amin, U Bakowsky, SA Fahmy - Pharmaceutics, 2023 - mdpi.com
Cancer is a global health burden and is one of the leading causes of death. Photodynamic
therapy (PDT) is considered an alternative approach to conventional cancer treatment. PDT …

[HTML][HTML] Box–Behnken design of thermo-responsive nano-liposomes loaded with a platinum (IV) anticancer complex: evaluation of cytotoxicity and apoptotic pathways …

NK Sedky, M Braoudaki, NK Mahdy, K Amin… - Nanoscale …, 2023 - pubs.rsc.org
Herein, thermo-responsive liposomes (TLs) loaded with Asp (Asp/TLs) were produced by
self-assembling DPPC, DSPE-PEG2000, and cholesterol. The preparation variables were …

[HTML][HTML] Recent advances in brain delivery of synthetic and natural nano therapeutics: Reviving hope for Alzheimer's disease patients

DS Nady, U Bakowsky, SA Fahmy - Journal of Drug Delivery Science and …, 2023 - Elsevier
As the globe's population increases, the incidences of Alzheimer's disease (AD) are steadily
increasing. AD represents the most common neurological disorder and constitutes 60–70 …

Newly Synthesized Anticancer Purine Derivatives Inhibiting p-EIF4E Using Surface-Modified Lipid Nanovesicles

RT Attia, MA Ewida, E Khaled, SA Fahmy, IM Fawzy - ACS omega, 2023 - ACS Publications
Translation of mRNA is one of the processes adopted by cancer cells to maintain survival via
phosphorylated (p)-eIF4E overexpression. Once p-eIF4E binds to the cap structure of …

[HTML][HTML] Facile sonochemically-assisted bioengineering of titanium dioxide nanoparticles and deciphering their potential in treating breast and lung cancers: biological …

NK Sedky, NK Mahdy, NM Abdel-Kader… - RSC …, 2024 - pubs.rsc.org
Combining sonochemistry with phytochemistry is a modern trend in the biosynthesis of
metallic nanoparticles (NPs), which contributes to the sustainability of chemical processes …

Antimicrobial Activities of Pistacia lentiscus Essential Oils Nanoencapsulated into Hydroxypropyl-beta-cyclodextrins

OAA Alabrahim, HMES Azzazy - ACS omega, 2024 - ACS Publications
The rising risks of food microbial contamination and foodborne pathogens resistance have
prompted an increasing interest in natural antimicrobials as promising alternatives to …

Exploring the potential of silymarin-loaded nanovesicles as an effective drug delivery system for cancer therapy: in vivo, in vitro, and in silico experiments

MR Hajinezhad, M Roostaee, Z Nikfarjam… - Naunyn-Schmiedeberg's …, 2024 - Springer
We aimed to perform a comprehensive study on the development and characterization of
silymarin (Syl)-loaded niosomes as potential drug delivery systems. The results demonstrate …

[HTML][HTML] Synergistic anticancer effect of Pistacia lentiscus essential oils and 5-Fluorouracil co-loaded onto biodegradable nanofibers against melanoma and breast …

OAA Alabrahim, HMES Azzazy - Discover Nano, 2024 - Springer
Chemoresistance and severe toxicities represent major drawbacks of chemotherapy.
Natural extracts, including the essential oils of Pistacia lentiscus (PLEO), exhibit substantial …

[HTML][HTML] Emerging tendencies for the nano-delivery of gambogic acid: a promising approach in oncotherapy

SA Fahmy, R Elghanam, G Rashid, RA Youness… - RSC …, 2024 - pubs.rsc.org
Despite the advancements in cancer therapies during the past few years, chemo/photo
resistance, severe toxic effects, recurrence of metastatic tumors, and non-selective targeting …

[HTML][HTML] Innovative microwave-assisted biosynthesis of copper oxide nanoparticles loaded with platinum (ii) based complex for halting colon cancer: cellular …

NK Sedky, IM Fawzy, A Hassan, NK Mahdy, RT Attia… - RSC …, 2024 - pubs.rsc.org
In the current study, we biosynthesized copper oxide NPs (CuO NPs) utilizing the essential
oils extracted from Boswellia carterii oleogum resin, which served as a bioreductant and …