Autism spectrum disorder: classification, diagnosis and therapy

SR Sharma, X Gonda, FI Tarazi - Pharmacology & therapeutics, 2018 - Elsevier
Abstract Autism Spectrum Disorder (ASD) refers to a group of neurodevelopmental disorders
including autism, Asperger's syndrome (AS) and pervasive developmental disorder-not …

[HTML][HTML] Evaluation of recent intranasal drug delivery systems to the central nervous system

TP Crowe, WH Hsu - Pharmaceutics, 2022 - mdpi.com
Neurological diseases continue to increase in prevalence worldwide. Combined with the
lack of modifiable risk factors or strongly efficacious therapies, these disorders pose a …

[HTML][HTML] Roles of oxytocin in stress responses, allostasis and resilience

Y Takayanagi, T Onaka - International journal of molecular sciences, 2021 - mdpi.com
Oxytocin has been revealed to work for anxiety suppression and anti-stress as well as for
psychosocial behavior and reproductive functions. Oxytocin neurons are activated by …

Listening to the autistic voice: Mental health priorities to guide research and practice in autism from a stakeholder-driven project

TW Benevides, SM Shore, K Palmer, P Duncan… - …, 2020 - journals.sagepub.com
Autistic adults are significantly more likely to experience co-occurring mental health
conditions such as depression and anxiety. Although intervention studies are beginning to …

[HTML][HTML] Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice

Y Yamamoto, M Liang, S Munesue, K Deguchi… - Communications …, 2019 - nature.com
Oxytocin sets the stage for childbirth by initiating uterine contractions, lactation and maternal
bonding behaviours. Mice lacking secreted oxcytocin (Oxt−/−, Cd38−/−) or its receptor …

Oxytocin improves intracerebral hemorrhage outcomes by suppressing neuronal pyroptosis and mitochondrial fission

M Yang, S Deng, J Jiang, M Tian, L Xiao, Y Gong - Stroke, 2023 - Am Heart Assoc
BACKGROUND: Intracerebral hemorrhage (ICH) causes severe sensorimotor dysfunction
and cognitive decline which are aggravated by secondary brain injury, yet there are no …

[HTML][HTML] Oxytocin as treatment for social cognition, not there yet

AM Erdozain, O Peñagarikano - Frontiers in Psychiatry, 2020 - frontiersin.org
In a short time, oxytocin has progressed from being a regular hormone involved in parturition
and breastfeeding to be possibly the neuromodulator that has gathered the most attention …

[HTML][HTML] Novel treatments for autism spectrum disorder based on genomics and systems biology

D Baribeau, E Anagnostou - Pharmacology & therapeutics, 2022 - Elsevier
Background Autism spectrum disorder (ASD) is a highly heterogeneous
neurodevelopmental disorder with a complex underlying genetic architecture. There are …

Linking oxytocin and arginine vasopressin signaling abnormalities to social behavior impairments in Prader-Willi syndrome

O Oztan, O Zyga, DEJ Stafford, KJ Parker - Neuroscience & Biobehavioral …, 2022 - Elsevier
Prader-Willi syndrome (PWS) is a genetic neurodevelopmental disorder. Global
hypothalamic dysfunction is a core feature of PWS and has been implicated as a driver of …

Routes of drug administration

ME Ruiz, S Scioli-Montoto - ADME Processes in Pharmaceutical Sciences …, 2024 - Springer
The systemic absorption of a drug depends on its physicochemical properties, the nature of
the dosage form on which it is included, and the anatomical and physiological …