Polyguluronic acid alleviates doxorubicin-induced cardiotoxicity by suppressing Peli1-NLRP3 inflammasome-mediated pyroptosis
E Zhang, C Shang, M Ma, X Zhang, Y Liu, S Song… - Carbohydrate …, 2023 - Elsevier
Polyguluronic acid (PG), a polysaccharide from alginate, possesses excellent bioactivities.
We prepared high-purity PG with 10.41 kDa molecular weight (Mw) and a 59 average …
We prepared high-purity PG with 10.41 kDa molecular weight (Mw) and a 59 average …
Fractionated whole body γ-irradiation aggravates arthritic severity via boosting NLRP3 and RANKL expression in adjuvant-induced arthritis model: the mitigative …
NM Thabet, MK Abdel-Rafei, MM Amin - Inflammopharmacology, 2023 - Springer
Rheumatoid arthritis (RA) is an autoimmune chronic inflammatory disease associated with
oxidative stress that causes excruciating pain, discomfort, and joint destruction. Ebselen …
oxidative stress that causes excruciating pain, discomfort, and joint destruction. Ebselen …
Recent developments in anti-inflammatory therapy
Advances in Anti-inflammatory Therapy explores the cutting-edge in anti-inflammation
therapy in clear and concise language, with insights from academia and industry. Sections …
therapy in clear and concise language, with insights from academia and industry. Sections …
Concerted regulation of OPG/RANKL/NF‑κB/MMP-13 trajectories contribute to ameliorative capability of prodigiosin and/or low dose γ-radiation against adjuvant …
MK Abdel-Rafei, NM Thabet, MM Amin - International …, 2022 - Elsevier
Background Prodigiosin (PDG) is a microbial red dye with antioxidant and anti-inflammatory
properties, although its effect on rheumatoid arthritis (RA) remains uncertain. Also, multiple …
properties, although its effect on rheumatoid arthritis (RA) remains uncertain. Also, multiple …
Total Saponins from Nigella glandulifera Seeds Ameliorate Adjuvant‐Induced Rheumatoid Arthritis in Rats by Inhibition of an Inflammatory Response and Bone …
L Zeng, C Li, H Jiang, Y Chen, Z Li… - BioMed Research …, 2021 - Wiley Online Library
Rheumatoid arthritis (RA) is a widespread inflammatory disease whose clinical
manifestations are joint swelling, pain, and disability, affecting approximately 1% of …
manifestations are joint swelling, pain, and disability, affecting approximately 1% of …
Evaluation of G2013 (α‐L‐guluronic acid) efficacy on PC‐3 cells through inhibiting the expression of inflammatory factors
Z Bagherian, A Mirshafiey… - Clinical and …, 2022 - Wiley Online Library
Given multiple treatment strategies for prostate cancer, its mortality rate is still high;
therefore, novel treatment strategies seem necessary. G2013 or α‐L‐guluronic acid is a new …
therefore, novel treatment strategies seem necessary. G2013 or α‐L‐guluronic acid is a new …
Clinical trials and future perspectives of antiinflammatory agents
Antiinflammatory drugs are used widely to reduce inflammation that is involved in various
diseases such as Alzheimer, Parkinson, rheumatoid arthritis, asthma, infectious diseases …
diseases such as Alzheimer, Parkinson, rheumatoid arthritis, asthma, infectious diseases …
The Efficacy of Two Specific Toll-Like Receptor 4 Antagonists (G2013 & M2000) In Clinical Inflammatory Disease
M Taeb, M Rahmani, L Sharifi… - Applied Sciences …, 2023 - hspublishing.org
Toll-like receptors (TLRs) are receptors of the innate immune system that detect pathogen-
associated molecular patterns and endogenous “danger” molecules. Among the family, the …
associated molecular patterns and endogenous “danger” molecules. Among the family, the …