[HTML][HTML] Lotus (Nelumbo nucifera Gaertn.) and Its Bioactive Phytocompounds: A Tribute to Cancer Prevention and Intervention

A Bishayee, PA Patel, P Sharma, S Thoutireddy, N Das - Cancers, 2022 - mdpi.com
Simple Summary The plant Nelumbo nucifera (Gaertn.), commonly known as lotus, sacred
lotus, Indian lotus, water lily, or Chinese water lily, is an aquatic perennial crop belonging to …

[HTML][HTML] Oxidative stress, hormones, and effects of natural antioxidants on intestinal inflammation in inflammatory bowel disease

DK Sahoo, RM Heilmann, B Paital, A Patel… - Frontiers in …, 2023 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic, relapsing gastrointestinal (GI) disorder
characterized by intestinal inflammation. The etiology of IBD is multifactorial and results from …

Combinatorial epigenetic mechanisms of sulforaphane, genistein and sodium butyrate in breast cancer inhibition

M Sharma, TO Tollefsbol - Experimental Cell Research, 2022 - Elsevier
Dietary phytochemicals are currently being studied with great interest due to their ability to
regulate the epigenome resulting in prevention of cancer. Some natural botanicals have …

Therapeutic effects of sulforaphane in ulcerative colitis: effect on antioxidant activity, mitochondrial biogenesis and DNA polymerization

A Alattar, R Alshaman, MMH Al-Gayyar - Redox Report, 2022 - Taylor & Francis
Objectives Ulcerative colitis (UC), an inflammatory bowel disease, affects mucosal lining of
colon leading to inflammation and ulcers. Sulforaphane is a natural compound obtained …

Targeting cellular senescence in cancer by plant secondary metabolites: A systematic review

S Fakhri, SZ Moradi, A Ash-Rafzadeh… - Pharmacological …, 2022 - Elsevier
Senescence suppresses tumor growth, while also developing a tumorigenic state in the
nearby cells that is mediated by senescence-associated secretory phenotypes (SASPs). The …

[HTML][HTML] Anti-angiogenic effects of natural compounds in diet-associated hepatic inflammation

S Novi, V Vestuto, P Campiglia, N Tecce, A Bertamino… - Nutrients, 2023 - mdpi.com
Alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are the most
common causes of chronic liver disease and are increasingly emerging as a global health …

Targeting transforming growth factor‐ß signalling for cancer prevention and intervention: Recent advances in developing small molecules of natural origin

D Tewari, A Priya, A Bishayee… - Clinical and …, 2022 - Wiley Online Library
Background Cancer is the world's second leading cause of death, but a significant
advancement in cancer treatment has been achieved within the last few decades. However …

[HTML][HTML] Brassica Genus Seeds: A Review on Phytochemical Screening and Pharmacological Properties

J Ayadi, M Debouba, R Rahmani, J Bouajila - Molecules, 2022 - mdpi.com
Traditionally, Brassica species are widely used in traditional medicine, human food, and
animal feed. Recently, special attention has been dedicated to Brassica seeds as source of …

Effects of Sulforaphane on SARS‑CoV‑2 infection and NF‑κB dependent expression of genes involved in the COVID‑19 'cytokine storm'

J Gasparello, G Marzaro, C Papi… - International …, 2023 - spandidos-publications.com
Since its spread at the beginning of 2020, the coronavirus disease 2019 (COVID‑19)
pandemic represents one of the major health problems. Despite the approval, testing, and …

Therapeutic advancements in targeting BCL-2 family proteins by epigenetic regulators, natural, and synthetic agents in cancer

A Sarkar, A Paul, T Banerjee, A Maji, S Saha… - European Journal of …, 2023 - Elsevier
Cancer is amongst the deadliest and most disruptive disorders, having a much higher death
rate than other diseases worldwide. Human cancer rates continue to rise, thereby posing the …