Role of sulforaphane in endoplasmic reticulum homeostasis through regulation of the antioxidant response

AH Dana, SP Alejandro - Life Sciences, 2022 - Elsevier
Nowadays, the nutraceutical agent sulforaphane (SFN) shows great versatility in turning on
different cellular responses. Mainly, this isothiocyanate acts as a master regulator of cellular …

[HTML][HTML] Sulforaphane suppresses paraquat-induced oxidative damage in bovine in vitro-matured oocytes through Nrf2 transduction pathway

Z Feng, T Wang, Y Sun, S Chen, H Hao, W Du… - Ecotoxicology and …, 2023 - Elsevier
Sulforaphane (SFN), a bioactive phytocompound extracted from cruciferous plants, has
received increasing attention due to its vital cytoprotective role in eliminating oxidative free …

[PDF][PDF] Developing multifunctional crops by engineering Brassicaceae glucosinolate pathways

H Qin, GJ King, P Borpatragohain, J Zou - Plant communications, 2023 - cell.com
Glucosinolates (GSLs), found mainly in species of the Brassicaceae family, are one of the
most well-studied classes of secondary metabolites. Produced by the action of myrosinase …

[HTML][HTML] The Impacts of the Emerging Climate Change on Broccoli (Brassica oleracea L. var. italica Plenck.) Crop

AS Siomos, K Koularmanis, P Tsouvaltzis - Horticulturae, 2022 - mdpi.com
Broccoli (Brassica oleracea L. var. italica Plenck.) is nowadays one of the most important
vegetable crops worldwide, with an increasing demand by the market, due to its high …

[HTML][HTML] Epigenetic Modifications Induced by the Gut Microbiota May Result from What We Eat: Should We Talk about Precision Diet in Health and Disease?

K Reva, J Laranjinha, BS Rocha - Metabolites, 2023 - mdpi.com
Diet is currently considered one of the most important adjustable determinants of human
health. The gut microbiota, the collection of microorganisms that inhabit (mainly) the distal …

Sulforaphane suppresses MCF-7 breast cancer cells growth via miR-19/PTEN axis to antagonize the effect of butyl benzyl phthalate

W Cao, X Lu, C Zhong, J Wu - Nutrition and Cancer, 2023 - Taylor & Francis
Sulforaphane (SFN), a major isothiocyanate found in cruciferous vegetables, reportedly
exerts extensive antitumor effects. Butyl benzyl phthalate (BBP), a widely used plasticizer …

Plant sources, extraction techniques, analytical methods, bioactivity, and bioavailability of sulforaphane: A review

X Men, X Han, G Oh, JH Im, J Lim, GH Cho… - Food Science and …, 2024 - Springer
Sulforaphane (SFN) is an isothiocyanate commonly found in cruciferous vegetables. It is
formed via the enzymatic hydrolysis of glucoraphanin by myrosinase. SFN exerts various …

[HTML][HTML] Broccoli sprouts and their influence on thyroid function in different in vitro and in vivo models

P Paśko, P Zagrodzki, K Okoń, E Prochownik… - Plants, 2022 - mdpi.com
Broccoli sprouts are a super vegetable; however, they have possible negative effects on
thyroid function, which is especially important for patients with hypothyroidism. As the data …

Phytochemicals for the prevention and treatment of pancreatic cancer: Current progress and future prospects

N Casarcia, P Rogers, E Guld, S Iyer… - British Journal of …, 2023 - Wiley Online Library
Pancreatic cancer is the third leading cause of cancer‐related deaths in the United States,
owing to its aggressive nature and suboptimal treatment options, emphasizing the need for …

[HTML][HTML] Isothiocyanates (ITCs) 1-(Isothiocyanatomethyl)-4-phenylbenzene and 1-Isothiocyanato-3, 5-bis (trifluoromethyl) benzene—Aldehyde Dehydrogenase (ALDH …

J Kryczka, J Kryczka, Ł Janczewski, A Gajda… - International Journal of …, 2022 - mdpi.com
One of the main treatment modalities for non-small-cell lung cancer (NSCLC) is cisplatin-
based chemotherapy. However, the acquisition of cisplatin resistance remains a major …