Vascular calcification in CKD-MBD: Roles for phosphate, FGF23, and Klotho
S Yamada, CM Giachelli - Bone, 2017 - Elsevier
Vascular calcification (VC) is highly prevalent in aging, diabetes mellitus, and chronic kidney
disease (CKD). VC is a strong predictor of cardiovascular morbidity and mortality in the CKD …
disease (CKD). VC is a strong predictor of cardiovascular morbidity and mortality in the CKD …
Valvular heart disease and calcification in CKD: more common than appreciated
Ischaemic heart disease, sudden cardiac death and arrhythmias, heart failure, stroke and
peripheral arterial disease make up> 50% of the causes of death in advanced chronic …
peripheral arterial disease make up> 50% of the causes of death in advanced chronic …
Hemodynamics and mechanobiology of aortic valve inflammation and calcification
K Balachandran, P Sucosky… - International journal of …, 2011 - Wiley Online Library
Cardiac valves function in a mechanically complex environment, opening and closing close
to a billion times during the average human lifetime, experiencing transvalvular pressures …
to a billion times during the average human lifetime, experiencing transvalvular pressures …
[HTML][HTML] Elevated cyclic stretch induces aortic valve calcification in a bone morphogenic protein-dependent manner
Calcified aortic valve (AV) cusps have increased expression of bone morphogenic proteins
(BMPs) and transforming growth factor-β1 (TGF-β1). Elevated stretch loading on the AV is …
(BMPs) and transforming growth factor-β1 (TGF-β1). Elevated stretch loading on the AV is …
Vascular calcification in chronic kidney disease
VC (vascular calcification) is highly prevalent in patients with CKD (chronic kidney disease),
but its mechanism is multifactorial and incompletely understood. In addition to increased …
but its mechanism is multifactorial and incompletely understood. In addition to increased …
Mechanistic insights into CKD-MBD-related vascular calcification and its clinical implications
Abstract Chronic Kidney Disease (CKD) is linked to a rising prevalence of morbidity and
mortality primarily from cardiovascular complications and is considered a high or very high …
mortality primarily from cardiovascular complications and is considered a high or very high …
Mineral metabolism and cardiovascular disease in CKD
H Fujii, N Joki - Clinical and experimental nephrology, 2017 - Springer
The mineral bone disorder of CKD, called Chronic Kidney Disease-Mineral and Bone
Disorder (CKD-MBD), has a major role in the etiology and progression of cardiovascular …
Disorder (CKD-MBD), has a major role in the etiology and progression of cardiovascular …
Markers of increased cardiovascular risk in patients with chronic kidney disease
A Gluba-Brzózka, M Michalska-Kasiczak… - Lipids in health and …, 2014 - Springer
Background Epidemiological studies have shown that chronic kidney disease (CKD) is an
important risk factor for atherosclerosis and cardiovascular disease (CAD). The aim of the …
important risk factor for atherosclerosis and cardiovascular disease (CAD). The aim of the …
Association of cardiac valvular calcifications and C-reactive protein with cardiovascular mortality in incident hemodialysis patients: a Japanese cohort study
H Takahashi, H Ishii, T Aoyama, D Kamoi… - American journal of …, 2013 - Elsevier
BACKGROUND: Cardiac valve calcification is seen frequently in patients undergoing
dialysis. Serum C-reactive protein (CRP) level also is reported to predict future …
dialysis. Serum C-reactive protein (CRP) level also is reported to predict future …
Chronic kidney disease and the pathophysiology of valvular heart disease
J Ternacle, N Côté, L Krapf, A Nguyen… - Canadian Journal of …, 2019 - Elsevier
Valvular heart calcification is common in patients with chronic kidney disease (CKD),
especially in those receiving hemodialysis therapy, and it is associated with poor prognosis …
especially in those receiving hemodialysis therapy, and it is associated with poor prognosis …