Magnetic nanoparticles and clusters for magnetic hyperthermia: Optimizing their heat performance and developing combinatorial therapies to tackle cancer

H Gavilán, SK Avugadda… - Chemical Society …, 2021 - pubs.rsc.org
Magnetic hyperthermia (MHT) is a therapeutic modality for the treatment of solid tumors that
has now accumulated more than 30 years of experience. In the ongoing MHT clinical trials …

Glioblastoma multiforme (GBM): An overview of current therapies and mechanisms of resistance

W Wu, JL Klockow, M Zhang, F Lafortune… - Pharmacological …, 2021 - Elsevier
Glioblastoma multiforme (GBM) is a WHO grade IV glioma and the most common malignant,
primary brain tumor with a 5-year survival of 7.2%. Its highly infiltrative nature, genetic …

New opportunities and old challenges in the clinical translation of nanotheranostics

PJ Gawne, M Ferreira, M Papaluca, J Grimm… - Nature reviews …, 2023 - nature.com
Nanoparticle-based systems imbued with both diagnostic and therapeutic functions, known
as nanotheranostics, have enabled remarkable progress in guiding focal therapy, inducing …

[HTML][HTML] Comprehensive understanding of magnetic hyperthermia for improving antitumor therapeutic efficacy

X Liu, Y Zhang, Y Wang, W Zhu, G Li, X Ma, Y Zhang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Magnetic hyperthermia (MH) has been introduced clinically as an alternative approach for
the focal treatment of tumors. MH utilizes the heat generated by the magnetic nanoparticles …

[HTML][HTML] Magnetic iron oxide nanoparticles for brain imaging and drug delivery

R Qiao, C Fu, H Forgham, I Javed, X Huang… - Advanced Drug Delivery …, 2023 - Elsevier
Central nervous system (CNS) disorders affect as many as 1.5 billion people globally. The
limited delivery of most imaging and therapeutic agents into the brain is a major challenge …

[HTML][HTML] Wireless on-demand drug delivery

SM Mirvakili, R Langer - Nature Electronics, 2021 - nature.com
Wireless on-demand drug delivery systems exploit exogenous stimuli—acoustic waves,
electric fields, magnetic fields and electromagnetic radiation—to trigger drug carriers. The …

[HTML][HTML] Pharmacokinetics of magnetic iron oxide nanoparticles for medical applications

J Nowak-Jary, B Machnicka - Journal of Nanobiotechnology, 2022 - Springer
Magnetic iron oxide nanoparticles (MNPs) have been under intense investigation for at least
the last five decades as they show enormous potential for many biomedical applications …

An injectable and active hydrogel induces mutually enhanced mild magnetic hyperthermia and ferroptosis

X Chen, H Wang, J Shi, Z Chen, Y Wang, S Gu, Y Fu… - Biomaterials, 2023 - Elsevier
Magnetic hyperthermia therapy (MHT) is a promising new modality to deal with solid tumors,
yet the low magnetic-heat conversion efficacy, magnetic resonance imaging (MRI) artifacts …

[HTML][HTML] Cancer therapy with iron oxide nanoparticles: Agents of thermal and immune therapies

F Soetaert, P Korangath, D Serantes, S Fiering… - Advanced drug delivery …, 2020 - Elsevier
Significant research and preclinical investment in cancer nanomedicine has produced
several products, which have improved cancer care. Nevertheless, there exists a perception …

Heating technology for malignant tumors: A review

HP Kok, ENK Cressman, W Ceelen… - International Journal …, 2020 - Taylor & Francis
The therapeutic application of heat is very effective in cancer treatment. Both hyperthermia,
ie, heating to 39–45° C to induce sensitization to radiotherapy and chemotherapy, and …