Psoriasis is an immune cell-mediated inflammatory skin disease. The interleukin (IL) 23/IL17
axis plays an important role in the development of psoriasis. The effectiveness of biologic …

Psoriasis is a chronic inflammatory skin disease characterized by scaly indurated erythema.
This disease impairs patients' quality of life enormously. Pathological findings demonstrate …

INTRODUCTION Human skin provides vital protection from water loss and from external
insult through structural adaptations and interplay with the innate and adaptive immune …

Dendritic cells (DCs) are potent and versatile antigen-presenting cells, and their ability to
migrate is key for the initiation of protective pro-inflammatory as well as tolerogenic immune …

The skin barrier is broadly composed of two elements—a physical barrier mostly localised in
the epidermis, and an immune barrier localised in both the dermis and epidermis. These two …

Psoriasis is a common inflammatory skin disease involving interactions between
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …

Many autoimmune disorders such as psoriasis lead to the alteration of skin components
which generally manifests as unwanted topical symptoms. One of the most widely approved …

Psoriasis is a chronic skin inflammatory disorder, the immune mechanism of which has been
profoundly elucidated in the past few years. The dominance of the interleukin (IL)‐23/IL‐17 …

CaMK4 has an important function in autoimmune diseases, and the contribution of CaMK4
in psoriasis remains obscure. Here, we show that CaMK4 expression is significantly …

Acute inflammation can either resolve through immunosuppression or persist, leading to
chronic inflammation. These transitions are driven by distinct molecular and metabolic …