[HTML][HTML] Brain manganese and the balance between essential roles and neurotoxicity

RC Balachandran, S Mukhopadhyay, D McBride… - Journal of Biological …, 2020 - ASBMB
Manganese (Mn) is an essential micronutrient required for the normal development of many
organs, including the brain. Although its roles as a cofactor in several enzymes and in …

[HTML][HTML] Molecular targets of manganese-induced neurotoxicity: A five-year update

AA Tinkov, MMB Paoliello, AN Mazilina… - International journal of …, 2021 - mdpi.com
Understanding of the immediate mechanisms of Mn-induced neurotoxicity is rapidly
evolving. We seek to provide a summary of recent findings in the field, with an emphasis to …

The large-scale period of atmospheric trace metal deposition to urban landscape trees as a biomonitor

K Isinkaralar - Biomass conversion and biorefinery, 2024 - Springer
Traffic emissions and industrial activities cause atmospheric contamination derived from
fossil fuels. The potential uptake of air pollutants affects the ecosystem and decreases air …

Dietary intake of cadmium, chromium, copper, manganese, selenium and zinc in a Northern Italy community

T Filippini, S Cilloni, M Malavolti, F Violi… - Journal of Trace …, 2018 - Elsevier
This study provides the dietary intakes of six trace elements (cadmium, chromium, copper,
manganese, selenium and zinc), generally characterized by both nutritional and …

[HTML][HTML] Manganese promotes α-synuclein amyloid aggregation through the induction of protein phase transition

B Xu, S Huang, Y Liu, C Wan, Y Gu, D Wang… - Journal of Biological …, 2022 - ASBMB
α-Synuclein (α-Syn) is the major protein component of Lewy bodies, a key pathological
feature of Parkinson's disease (PD). The manganese ion Mn 2+ has been identified as an …

[HTML][HTML] Consequences of disturbing manganese homeostasis

J Baj, W Flieger, A Barbachowska, B Kowalska… - International Journal of …, 2023 - mdpi.com
Manganese (Mn) is an essential trace element with unique functions in the body; it acts as a
cofactor for many enzymes involved in energy metabolism, the endogenous antioxidant …

[HTML][HTML] Applications and biological activity of nanoparticles of manganese and manganese oxides in in vitro and in vivo models

Z Sobańska, J Roszak, K Kowalczyk, M Stępnik - Nanomaterials, 2021 - mdpi.com
The expanding applications of nanotechnology seem to be a response to many
technological, environmental, and medical challenges. The unique properties of …

[HTML][HTML] Manganese suppresses oxidative stress, inflammation and caspase-3 activation in rats exposed to chlorpyrifos

SE Owumi, UJ Dim - Toxicology Reports, 2019 - Elsevier
The present study investigated the individual and combined impact of organophosphorus
pesticide chlorpyrifos (CPF) and manganese (Mn), a naturally occurring trace metal, on …

[HTML][HTML] Mechanisms of Co, Ni, and Mn toxicity: From exposure and homeostasis to their interactions with and impact on lipids and biomembranes

K Sule, J Umbsaar, EJ Prenner - Biochimica et Biophysica Acta (BBA) …, 2020 - Elsevier
Anthropogenic activity has increased human exposure to metals and resulted in metal
induced toxicity. Essential trace elements like cobalt (Co), nickel (Ni), and manganese (Mn) …

Exposing the role of metals in neurological disorders: a focus on manganese

H Kim, FE Harrison, M Aschner, AB Bowman - Trends in molecular …, 2022 - cell.com
Metals are ubiquitous chemical entities involved in a myriad of biological processes. Despite
their integral role in sustaining life, overexposure can lead to deleterious neurological …