Neuropeptide system regulation of prefrontal cortex circuitry: implications for neuropsychiatric disorders
Neuropeptides, a diverse class of signaling molecules in the nervous system, modulate
various biological effects including membrane excitability, synaptic transmission and …
various biological effects including membrane excitability, synaptic transmission and …
Development, diversity, and death of MGE-derived cortical interneurons
RH Williams, T Riedemann - International Journal of Molecular Sciences, 2021 - mdpi.com
In the mammalian brain, cortical interneurons (INs) are a highly diverse group of cells. A key
neurophysiological question concerns how each class of INs contributes to cortical circuit …
neurophysiological question concerns how each class of INs contributes to cortical circuit …
Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice
Abstract NMDA receptor (NMDAR) and GABA neuronal dysfunctions are observed in animal
models of autism spectrum disorders, but how these dysfunctions impair social cognition …
models of autism spectrum disorders, but how these dysfunctions impair social cognition …
The maternal brain is more flexible and responsive at rest: effective connectivity of the parental caregiving network in postpartum mothers
The field of neuroscience has largely overlooked the impact of motherhood on brain function
outside the context of responses to infant stimuli. Here, we apply spectral dynamic causal …
outside the context of responses to infant stimuli. Here, we apply spectral dynamic causal …
CB1R dysfunction of inhibitory synapses in the ACC drives chronic social isolation stress-induced social impairments in male mice
B Guo, K Xi, H Mao, K Ren, H Xiao, ND Hartley… - Neuron, 2024 - cell.com
Social isolation is a risk factor for multiple mood disorders. Specifically, social isolation can
remodel the brain, causing behavioral abnormalities, including sociability impairments …
remodel the brain, causing behavioral abnormalities, including sociability impairments …
Neurochemical alterations in social anxiety disorder (SAD): a systematic review of proton magnetic resonance spectroscopic studies
S Elsaid, DS Rubin-Kahana, S Kloiber… - International Journal of …, 2022 - mdpi.com
(1) Objective: Considering that current knowledge of mechanisms involved in the molecular
pathogenesis of Social Anxiety Disorder (SAD) is limited, we conducted a systematic review …
pathogenesis of Social Anxiety Disorder (SAD) is limited, we conducted a systematic review …
Neuropeptide Y reduces social fear in male mice: Involvement of Y1 and Y2 Receptors in the dorsolateral septum and central amygdala
J Kornhuber, I Zoicas - International journal of molecular sciences, 2021 - mdpi.com
Neuropeptide Y (NPY) has anxiolytic-like effects and facilitates the extinction of cued and
contextual fear in rodents. We previously showed that intracerebroventricular administration …
contextual fear in rodents. We previously showed that intracerebroventricular administration …
Differences in mGluR5 Availability Depending on the Level of Social Avoidance in Drug-Naïve Young Patients with Major Depressive Disorder
JH Kim, YH Joo, YD Son, HK Kim… - … Disease and Treatment, 2022 - Taylor & Francis
Background Previous research has shown that metabotropic glutamate receptor-5 (mGluR5)
signaling is significantly involved in social avoidance. We investigated the relationship …
signaling is significantly involved in social avoidance. We investigated the relationship …
Neural circuits underlying social fear in rodents: An integrative computational model
V Alfieri, A Mattera, G Baldassarre - Frontiers in systems neuroscience, 2022 - frontiersin.org
Social avoidance in rodents arises from a complex interplay between the prefrontal cortex
and subcortical structures, such as the ventromedial hypothalamus and the dorsal …
and subcortical structures, such as the ventromedial hypothalamus and the dorsal …
The maternal brain is more flexible and responsive at rest: effective connectivity of the parental caregiving network in postpartum mothers
The field of neuroscience has largely overlooked the impact of motherhood on brain function
outside the context of responses to infant stimuli. Here, we apply spectral dynamic causal …
outside the context of responses to infant stimuli. Here, we apply spectral dynamic causal …