Nerve Growth Factor and the Role of Inflammation in Tumor Development

G Ferraguti, S Terracina, L Tarani, F Fanfarillo… - Current Issues in …, 2024 - mdpi.com
Nerve growth factor (NGF) plays a dual role both in inflammatory states and cancer, acting
both as a pro-inflammatory and oncogenic factor and as an anti-inflammatory and pro …

Optimizing Antimicrobial Peptide Design: Integration of Cell-Penetrating Peptides, Amyloidogenic Fragments, and Amino Acid Residue Modifications

SV Kravchenko, PA Domnin, SY Grishin… - International Journal of …, 2024 - mdpi.com
The escalating threat of multidrug-resistant pathogens necessitates innovative approaches
to combat infectious diseases. In this study, we examined peptides R23FS*, V31KS*, and …

Binding Dynamics of a Stapled Peptide Targeting the Transcription Factor NF− Y

C Durukan, F Arbore, R Klintrot, C Bigiotti… - …, 2024 - Wiley Online Library
Transcription factors (TFs) play a central role in gene regulation, and their malfunction can
result in a plethora of severe diseases. TFs are therefore interesting therapeutic targets, but …