Neurons in the suprachiasmatic nucleus (SCN) function as part of a central timing circuit that
drives daily changes in our behaviour and underlying physiology. A hallmark feature of SCN …

Neuronal activation induces rapid transcription of immediate early genes (IEGs) and longer-
term chromatin remodeling around secondary response genes (SRGs). Here, we use high …

Although the critical role for epigenetic mechanisms in development and cell differentiation
has long been appreciated, recent evidence reveals that these mechanisms are also …

Reference-quality genomes are expected to provide a resource for studying gene structure,
function, and evolution. However, often genes of interest are not completely or accurately …

Alzheimer's disease (AD) is the most common cause of dementia in older adults.
Neuropathological and imaging studies have demonstrated a progressive and stereotyped …

The mammalian brain exhibits diverse types of neural plasticity, including activity-dependent
neurogenesis in the adult hippocampus. How transient activation of mature neurons leads to …

Rhododendron delavayi Franch. is globally famous as an ornamental plant. Its distribution in
southwest China covers several different habitats and environments. However, not much …

Excessive glucocorticoid exposure during chronic stress causes synapse loss and learning
impairment. Under normal physiological conditions, glucocorticoid activity oscillates in …

Adaptation to different levels of illumination is central to the function of the retina. Here, we
demonstrate that levels of the miR-183/96/182 cluster, miR-204, and miR-211 are regulated …

MicroRNAs (miRNAs) are emerging as key modulators of post-transcriptional gene
regulation in a plethora of tissues, including the nervous system. Recent evidence points to …