The highly potent vanilloid receptor (VR) agonist resiniferatoxin has been radiolabeled with
125I, and the pharmacology to the cloned rodent VR, VR1, and the endogenous VR in rat …

Capsiate is a capsaicin-like ingredient of a non-pungent cultivar of red pepper, CH-19
sweet. To elucidate the mechanisms underlying the non-pungency of capsiate, we …

We investigated the effects of a single oral administra-tion of capsiate, which is found in the
fruits of a non-pungent cultivar of pepper, CH-19 Sweet, and has the same structure as …

The perception of pain throughout the body arises when neural signals originating from the
terminals of nociceptors are propagated to second-order neurons in the spinal cord or …

Cannabinoids can evoke antihyperalgesia and antinociception at a peripheral site of action.
However, the signaling pathways mediating these effects are not clearly understood. We …

Omega‐3 (n‐3) fatty acids are essential for proper neuronal function, and they possess
prominent analgesic properties, yet their underlying signalling mechanisms are unclear …

We investigated the effect of changing the length and degree of unsaturation of the fatty acyl
chain of N-(3-methoxy-4-hydroxy)-benzyl-cis-9-octadecenoamide (olvanil), a ligand of …

Although the cannabinoid agonists R-(+)-(2, 3-dihydro-5-methyl-3-[(4-morpholinyl) methyl]
pyrol [1, 2, 3-de]-1, 4-benzoxazin-6-yl)-(1-naphthalenyl) methanone mesylate [WIN 55,212-2 …

The chemical similarity between some synthetic agonists of vanilloid receptors, such as
olvanil (N-vanillyl-cis-9-octadecenoamide), and theendocannabinoid'anandamide …

Carstens, E., Nicole Kuenzler, and HO Handwerker. Activation of neurons in rat trigeminal
subnucleus caudalis by different irritant chemicals applied to oral or ocular mucosa. J …