BACKGROUND Advanced maternal age is associated with reduced fertility and adverse
pregnancy outcomes. This review details recent developments in our understanding of the …

With extended periods of time following ovulation, the metaphase II stage oocyte
experiences deterioration in quality referred to as post-ovulatory oocyte ageing. Post …

Female aging is one of the most important factors that impacts human reproduction. With
aging, there is a natural decline in female fertility. The decrease in fertility is slow and steady …

It is well known that maternal ageing not only causes increased spontaneous abortion and
reduced fertility, but it is also a high genetic disease risk. Although assisted reproductive …

Introduction: Oocyte quality and fertility decline with advanced maternal age. During
maturation within the ovarian follicle, the oocyte relies on the associated somatic cells …

Abstract Nicotinamide adenine dinucleotide (NAD+), a crucial coenzyme in cellular redox
reactions, is closely associated with age-related functional degeneration and metabolic …

Ovarian reserve is essential for fertility and influences healthy aging in women. Advanced
maternal age correlates with the progressive loss of both the quantity and quality of oocytes …

Sphingolipids are a class of essential lipids implicated in constructing cellular membranes
and regulating nearly all cellular functions. Sphingolipid metabolic network is centered with …

Lipids are the building blocks of cellular membranes and are synthesized at distinct parts of
the cell. A precise control of lipid synthesis and distribution is crucial for cell function and …

L-carnitine (LC) is well known for its antioxidant activity. In this study, we explored the
potential mechanistic effects of LC supplementation on aged bovine oocytes in vitro. We …