G‐quadruplexes are four‐stranded helical nucleic acid structures characterized by stacked
tetrads of guanosine bases. These structures are widespread throughout mammalian …

Guanine (G)-rich nucleic acid sequences can form diverse G-quadruplex structures located
in functionally significant genome regions, exerting regulatory control over essential …

The interactions of intermolecular G-quadruplex RNA and small molecules have been
investigated by computational studies. Various anthraquinone, bisbenzimidazole, and …

RNA structures are essential to support RNA functions and regulation in various biological
processes. Recently, a range of novel technologies have been developed to decode …

RNA G-quadruplexes (rG4s) are emerging structural motifs that are of pivotal importance in
chemistry and biology; however, the current structural information of rG4s is limited, with …

Long non-coding RNAs (lncRNAs) have emerged as auxiliary regulators of gene expression
influencing tumor microenvironment, metastasis and radio-resistance in cancer. The …

During translation, intracellular mRNA folds co-transcriptionally and must refold following the
passage of ribosome. The mRNAs can be entrapped in metastable structures during these …

Glaucoma is a heterogenous, chronic, progressive group of eye diseases, which results in
irreversible loss of vision. There are several types of glaucoma, whereas the primary open …

A common pathological feature of RNAs containing expanded repeat sequences is their
propensity to aggregate in cells. While some repeat RNA aggregates have been shown to …

Abstract The G-quadruplex (G4-DNA or G4) is a secondary DNA structure formed by DNA
sequences containing multiple runs of guanines. While it is now firmly established that …