[HTML][HTML] WHF IASC roadmap on Chagas disease

LE Echeverría, R Marcus, G Novick, S Sosa-Estani… - Global …, 2020 - ncbi.nlm.nih.gov
Background: Chagas Disease is a neglected tropical disease caused by the protozoan
Trypanosoma cruzi, with some of the most serious manifestations affecting the …

Central nervous system commitment in Chagas disease

Y Useche, AR Pérez, J De Meis, A Bonomo… - Frontiers in …, 2022 - frontiersin.org
The involvement of the central nervous system (CNS) during human acute and chronic
Chagas disease (CD) has been largely reported. Meningoencephalitis is a frequent finding …

What to expect and when: benznidazole toxicity in chronic Chagas' disease treatment

E Aldasoro, E Posada… - Journal of …, 2018 - academic.oup.com
Background Benznidazole is one of the two most effective antiparasitic drugs for Chagas'
disease treatment. However, knowledge about its toxicity profile is mostly based on post …

Understanding the oral transmission of Trypanosoma cruzi as a veterinary and medical foodborne zoonosis

N Velásquez-Ortiz, JD Ramírez - Research in veterinary science, 2020 - Elsevier
Chagas disease is a neglected tropical disease transmitted by the protozoan Trypanosoma
cruzi that lately has been highlighted because several outbreaks attributed to oral …

A systematic review of historical and current trends in Chagas disease

DA Álvarez-Hernández… - Therapeutic …, 2021 - journals.sagepub.com
Introduction: Chagas disease (CD) is caused by Trypanosoma cruzi. When acquired, the
disease develops in stages. For diagnosis, laboratory confirmation is required, and an …

Animal models of Chagas disease and their translational value to drug development

E Chatelain, I Scandale - Expert Opinion on Drug Discovery, 2020 - Taylor & Francis
Introduction American trypanosomiasis, better known as Chagas disease, is a global public
health issue. Current treatments targeting the causative parasite, Trypanosoma cruzi, are …

[HTML][HTML] Trypanosoma cruzi, beyond the dogma of non-infection in birds

F Martínez-Hernández, B Oria-Martínez… - Infection, Genetics and …, 2022 - Elsevier
Trypanosoma cruzi is a protozoan parasite responsible for Chagas disease affecting seven
million people. The disease cycle is maintained between Triatominae insects and Mammalia …

Identification of the parasite, Trypanosoma cruzi, in multiple tissues of epidemiological significance in the Virginia opossum (Didelphis virginiana): Implications for …

CW Torhorst, ZS White, CR Bhosale… - PLOS Neglected …, 2022 - journals.plos.org
Background Trypanosoma cruzi, a parasitic protozoan, is endemic to the Americas and the
causative agent of Chagas disease in humans. In South America, opossums facilitate …

Resveratrol and curcumin for Chagas disease treatment—a systematic review

CHL Imperador, CB Scarim, PL Bosquesi, JR Lopes… - Pharmaceuticals, 2022 - mdpi.com
Chagas disease (CD) is a neglected protozoan infection caused by Trypanosoma cruzi,
which affects about 7 million people worldwide. There are two available drugs in …

The importance of estimating the burden of disease from foodborne transmission of Trypanosoma cruzi

LJ Robertson, AH Havelaar, KH Keddy… - PLOS Neglected …, 2024 - journals.plos.org
Chagas disease (ChD), caused by infection with the flagellated protozoan, Trypanosoma
cruzi, has a complicated transmission cycle with many infection routes. These include vector …