Applications of nanotechnologies for miRNA-based cancer therapeutics: current advances and future perspectives

LA Bravo-Vázquez, A Méndez-García… - … in Bioengineering and …, 2023 - frontiersin.org
MicroRNAs (miRNAs) are short (18–25 nt), non-coding, widely conserved RNA molecules
responsible for regulating gene expression via sequence-specific post-transcriptional …

The Regulatory Role of MicroRNAs in Obesity and Obesity-Derived Ailments

JA Benavides-Aguilar, A Torres-Copado… - Genes, 2023 - mdpi.com
Obesity is a condition that is characterized by the presence of excessive adipose tissue in
the body. Obesity has become one of the main health concerns worldwide since it can lead …

Exploring the potential role of circulating microRNAs as biomarkers for predicting clinical response to neoadjuvant therapy in breast cancer

LM Ruiz-Manriquez, C Villarreal-Garza… - International Journal of …, 2023 - mdpi.com
Breast cancer (BC) is a leading cause of cancer-related deaths among women worldwide.
Neoadjuvant therapy (NAT) is increasingly being used to reduce tumor burden prior to …

Exploring the therapeutic significance of microRNAs and lncRNAs in kidney diseases

LA Bravo-Vázquez, S Paul, MG Colín-Jurado… - Genes, 2024 - mdpi.com
MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are two crucial classes of
transcripts that belong to the major group of non-coding RNAs (ncRNAs). These RNA …

Non-coding RNAs and human diseases: current status and future perspectives

J Niderla-Bielińska, E Jankowska-Steifer… - International journal of …, 2023 - mdpi.com
Non-coding RNAs (ncRNAs) are a family of RNA molecules that, unlike messenger RNAs,
are not templates for protein synthesis but have an essential or regulatory role in this …

Functional and Potential Therapeutic Implication of MicroRNAs in Pancreatic Cancer

A Pal, A Ojha, J Ju - International Journal of Molecular Sciences, 2023 - mdpi.com
The alarmingly low five-year survival rate for pancreatic cancer presents a global health
challenge, contributing to about 7% of all cancer-related deaths. Late-stage diagnosis and …

The mechanisms and diagnostic potential of lncRNAs, miRNAs, and their related signaling pathways in cervical cancer

Y Xu, Y Sun, X Song, J Ren - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Cervical cancer (CC), the fourth most prevalent type of cancer among women worldwide, is
associated with high rates of morbidity and mortality. Due to the long period of latency in CC …

Role of interleukins in inflammation-mediated tumor immune microenvironment modulation in colorectal cancer pathogenesis

SM Jain, D Deka, A Das, S Paul, S Pathak… - Digestive Diseases and …, 2023 - Springer
Introduction Tumor cells invade and spread through a procedure termed as epithelial-to-
mesenchymal cell transition (EMT). EMT is triggered by any alterations in the genes that …

The Expanding Roles of Long Non‐Coding RNAs in Pancreatic Cancer

Y Yan, D Wu, L Yang, J Han, Y Liu… - Advanced …, 2023 - Wiley Online Library
Pancreatic cancer is a clinically challenging disease with a poor survival rate and is one of
the leading causes of cancer‐related morbidity. It is highly resistant to treatment and …

Oncogenic and anticancer roles of miRNAs in colorectal cancer: A review

SA Mohammadi Bondarkhilli, M Kordkatouli… - Micro Nano Bio …, 2024 - mnba-journal.com
Colorectal cancer (CRC) is one of the most dangerous cancers that occur in colon or rectum
epithelial cells. Some studies disclose that CRC not only is the third most deadly cancer …