[HTML][HTML] A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia

AJ McGuinness, JA Davis, SL Dawson… - Molecular …, 2022 - nature.com
The emerging understanding of gut microbiota as 'metabolic machinery'influencing many
aspects of physiology has gained substantial attention in the field of psychiatry. This is …

Dopamine, immunity, and disease

B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - ASPET
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Epidemiology and risk factors for bipolar disorder

TA Rowland, S Marwaha - Therapeutic advances in …, 2018 - journals.sagepub.com
Bipolar disorder is a multifactorial illness with uncertain aetiology. Knowledge of potential
risk factors enables clinicians to identify patients who are more likely to develop bipolar …

Antipsychotics: mechanisms underlying clinical response and side-effects and novel treatment approaches based on pathophysiology

SJ Kaar, S Natesan, R Mccutcheon, OD Howes - Neuropharmacology, 2020 - Elsevier
Antipsychotic drugs are central to the treatment of schizophrenia and other psychotic
disorders but are ineffective for some patients and associated with side-effects and …

[HTML][HTML] Neuroinflammation in bipolar depression

F Benedetti, V Aggio, ML Pratesi, G Greco… - Frontiers in …, 2020 - frontiersin.org
Bipolar disorder (BD) is a leading cause of worldwide disability among mood disorders.
Pathological mechanisms are still vastly unclear, and current treatments with conventional …

Opposite effects of dopamine and serotonin on resting-state networks: review and implications for psychiatric disorders

B Conio, M Martino, P Magioncalda, A Escelsior… - Molecular …, 2020 - nature.com
Alterations in brain intrinsic activity—as organized in resting-state networks (RSNs) such as
sensorimotor network (SMN), salience network (SN), and default-mode network (DMN) …

[HTML][HTML] The emerging neurobiology of bipolar disorder

PJ Harrison, JR Geddes, EM Tunbridge - Trends in neurosciences, 2018 - cell.com
Bipolar disorder (BD) is a leading cause of global disability. Its biological basis is unknown,
and its treatment unsatisfactory. Here, we review two recent areas of progress. First, the …

Circadian rhythm disturbances in mood disorders: insights into the role of the suprachiasmatic nucleus

CA Vadnie, CA McClung - Neural plasticity, 2017 - Wiley Online Library
Circadian rhythm disturbances are a common symptom among individuals with mood
disorders. The suprachiasmatic nucleus (SCN), in the ventral part of the anterior …

[HTML][HTML] Circadian rhythms and mood disorders: Time to see the light

HK Dollish, M Tsyglakova, CA McClung - Neuron, 2024 - cell.com
The importance of time is ever prevalent in our world, and disruptions to the normal
light/dark and sleep/wake cycle have now become the norm rather than the exception for a …

[HTML][HTML] Pathophysiological bases of comorbidity in migraine

C Altamura, I Corbelli, M De Tommaso… - Frontiers in human …, 2021 - frontiersin.org
Despite that it is commonly accepted that migraine is a disorder of the nervous system with a
prominent genetic basis, it is comorbid with a plethora of medical conditions. Several studies …