Background Increasing evidence demonstrates a phenotypic plasticity of endothelial cells
(ECs). Endothelial-to-mesenchymal transition (EndMT) contributes to the development of …

Ischemia/reperfusion injury (IRI) is a central phenomenon in kidney transplantation and AKI.
Integrity of the renal peritubular capillary network is an important limiting factor in the …

Chronic kidney disease (CKD) has reached worldwide epidemic proportions and
desperately needs new therapies. Peritubular capillary (PTC) rarefaction, together with …

Previously, we identified plasma microRNA (miR) profiles that associate with markers of
microvascular injury in patients with diabetic nephropathy (DN). However, miRs circulate in …

Abstract Aims MicroRNA-126 (miR-126), which is enriched in endothelial cells, plays a role
in angiogenesis. Based on the seed sequence, miR-126 can also be predicted to regulate …

Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid decline in renal
function, and is associated with a high risk of death. Many pathological changes happen in …

Periodontal diseases are predisposing factors to the development of many systemic
disorders, which is often initiated via leukocyte infiltration and vascular inflammation. These …

Аннотация В статье обсуждаются теоретические и методологические подходы к
описанию системного воспаления как общепатологического процесса. Указывается, что …

Endothelial cells are the main component of the blood-brain barrier (BBB), a vital structure
for maintaining brain homeostasis that is seriously disrupted in various neurological …

Vascular endothelial growth factor antagonism with angiogenesis inhibitors in cancer
patients induces a 'preeclampsia-like'syndrome including hypertension, proteinuria and …