Most bacteria and archaea possess multiple antiviral defence systems that protect against
infection by phages, archaeal viruses and mobile genetic elements. Our understanding of …

The genus Pseudomonas hosts an extensive genetic diversity and is one of the largest
genera among Gram-negative bacteria. Type strains of Pseudomonas are well known to …

In the modern genomic era, scientists without extensive bioinformatic training need to apply
high-power computational analyses to critical tasks like phage genome annotation. At the …

We have developed a mouse DNA methylation array that contains 296,070 probes
representing the diversity of mouse DNA methylation biology. We present a mouse …

Maximal growth rate is a basic parameter of microbial lifestyle that varies over several orders
of magnitude, with doubling times ranging from a matter of minutes to multiple days. Growth …

INTRODUCTION Variola virus (VARV), the causative agent of smallpox, is estimated to have
killed between 300 million and 500 million people in the 20 th century and was …

Simple Summary Due to the development of high-throughput sequencing technologies,
computational genome annotation of sequences has become one of the principal research …

For the past 20 years, the Clusters of Orthologous Genes (COG) database had been a
popular tool for microbial genome annotation and comparative genomics. Initially created for …

Secondary metabolites produced by microorganisms are the main source of bioactive
compounds that are in use as antimicrobial and anticancer drugs, fungicides, herbicides and …

The fast-growing Gram-negative bacterium Vibrio natriegens is an attractive microbial
system for molecular biology and biotechnology due to its remarkably short generation time …