Acute kidney injury (AKI) and chronic kidney disease (CKD) are interconnected conditions,
and CKD is projected to become the fifth leading global cause of death by 2040. New …

Ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI). The kidney
is susceptible to IRI under several clinical conditions, including hypotension, sepsis, and …

Diabetic nephropathy (DN) is a common complication of diabetes mellitus. While there has
been a great advance in our understanding of the pathogenesis of DN, no effective …

Spinal cord injury (SCI) is a devastating injury that may result in permanent motor
impairment. The active ingredients of medications are unable to reach the affected area due …

Background: In 2004, the term acute kidney injury (AKI) was introduced with the intention of
broadening our understanding of rapid declines in renal function and to replace the …

Acute kidney injury (AKI) is becoming a public health problem worldwide. AKI is usually
considered a complication of lung, heart, liver, gut, and brain disease, but recent findings …

Methods and Results: Mice were fed with either a control diet or diet enriched with
dicarboxylic acids, which are peroxisome-specific FAO substrates, then subjected to either …

Mitochondrial antiviral signaling protein (MAVS) is a key innate immune adaptor on the outer
mitochondrial membrane that acts as a switch in the immune signal transduction response to …

Kidney injury and repair are accompanied by significant disruptions in metabolic pathways,
leading to renal cell dysfunction and further contributing to the progression of renal …

Abstract AMP-activated protein kinase (5'-adenosine monophosphate-activated protein
kinase, AMPK)/mammalian target of rapamycin (mTOR) is an important signaling pathway …