When a molecule absorbs a photon of appropriate energy, a chain of photophysical events
ensues, such as internal conversion or vibrational relaxation (loss of energy in the absence …

Fluorescence sampling of cellular function is widely used in all aspects of biology, allowing
the visualization of cellular and sub-cellular biological processes with spatial resolutions in …

There is a wealth of new fluorescent reporter technologies for tagging of many cellular and
subcellular processes in vivo. This imposed contrast is now captured with an increasing …

Fast tracking of biological dynamics across multiple murine organs using the currently
commercially available whole-body preclinical imaging systems is hindered by their limited …

We present three-dimensional (3D) in vivo images of human breast cancer based on
fluorescence diffuse optical tomography (FDOT). To our knowledge, this work represents the …

Emerging fluorescence and bioluminescence tomography approaches have several
common, yet several distinct features from established emission tomographies of PET and …

A promising method to incorporate tissue structural information into the reconstruction of
diffusion-based fluorescence imaging is introduced. The method regularizes the inversion …

A multichannel spectrally resolved optical tomography system to image molecular targets in
small animals from within a clinical MRI is described. Long source/detector fibers operate in …

Fluorescence tomography of diffuse media can yield optimal three-dimensional imaging
when multiple projections over 360° geometries are captured, compared with limited …

Optical molecular imaging in small animals harnesses the power of highly specific and
biocompatible contrast agents for drug development and disease research,,,,,,. However, the …