Left ventricular remodeling after myocardial infarction: from physiopathology to treatment
Myocardial infarction (MI) is the leading cause of death and morbidity worldwide, with an
incidence relatively high in developed countries and rapidly growing in developing …
incidence relatively high in developed countries and rapidly growing in developing …
Cardiac remodeling after myocardial infarction: functional contribution of microRNAs to inflammation and fibrosis
After an ischemic injury, the heart undergoes a complex process of structural and functional
remodeling that involves several steps, including inflammatory and fibrotic responses. In this …
remodeling that involves several steps, including inflammatory and fibrotic responses. In this …
Exercise training alleviates cardiac fibrosis through increasing fibroblast growth factor 21 and regulating TGF-β1-Smad2/3-MMP2/9 signaling in mice with myocardial …
Y Ma, Y Kuang, W Bo, Q Liang, W Zhu, M Cai… - International Journal of …, 2021 - mdpi.com
Exercise training has been reported to alleviate cardiac fibrosis and ameliorate heart
dysfunction after myocardial infarction (MI), but the molecular mechanism is still not fully …
dysfunction after myocardial infarction (MI), but the molecular mechanism is still not fully …
Calycosin reduces myocardial fibrosis and improves cardiac function in post-myocardial infarction mice by suppressing TGFBR1 signaling pathways
G Chen, H Xu, T Xu, W Ding, G Zhang, Y Hua, Y Wu… - Phytomedicine, 2022 - Elsevier
Background Excessive myocardial fibrosis is the pathological basis of heart failure following
myocardial infarction (MI). Although calycosin improves cardiac function, its effect on cardiac …
myocardial infarction (MI). Although calycosin improves cardiac function, its effect on cardiac …
Extracellular vesicles mediate biological information delivery: A double-edged sword in cardiac remodeling after myocardial infarction
P Cheng, X Wang, Q Liu, T Yang, H Qu… - Frontiers in …, 2023 - frontiersin.org
Acute myocardial infarction (AMI) is a severe ischemic disease with high morbidity and
mortality worldwide. Maladaptive cardiac remodeling is a series of abnormalities in cardiac …
mortality worldwide. Maladaptive cardiac remodeling is a series of abnormalities in cardiac …
KATP channels are regulators of programmed cell death and targets for the creation of novel drugs against ischemia/reperfusion cardiac injury
LN Maslov, SV Popov, NV Naryzhnaya… - Fundamental & …, 2023 - Wiley Online Library
Background The use of percutaneous coronary intervention (PCI) in patients with ST‐
segment elevation myocardial infarction (STEMI) is associated with a mortality rate of 5 …
segment elevation myocardial infarction (STEMI) is associated with a mortality rate of 5 …
PPAR alpha activation by clofibrate alleviates ischemia/reperfusion injury in metabolic syndrome rats by decreasing cardiac inflammation and remodeling and by …
M Sánchez-Aguilar, L Ibarra-Lara… - International Journal of …, 2023 - mdpi.com
Metabolic syndrome (MetS) is a cluster of factors that increase the risk of developing
diabetes, stroke, and heart failure. The pathophysiology of injury by ischemia/reperfusion …
diabetes, stroke, and heart failure. The pathophysiology of injury by ischemia/reperfusion …
Engineering of MSCs sheet for the prevention of myocardial ischemia and for left ventricle remodeling
D Chang, X Yang, S Fan, T Fan, M Zhang… - Stem Cell Research & …, 2023 - Springer
Tissue engineering combines cell biology and material science to construct tissues or
organs for disease modeling, drug testing, and regenerative medicine. The cell sheet is a …
organs for disease modeling, drug testing, and regenerative medicine. The cell sheet is a …
The emerging importance of immunophilins in fibrosis development
Immunophilins are a family of proteins encompassing FK506-binding proteins (FKBPs) and
cyclophilins (Cyps). FKBPs and Cyps exert peptidyl-prolyl cis-trans isomerase (PPIase) …
cyclophilins (Cyps). FKBPs and Cyps exert peptidyl-prolyl cis-trans isomerase (PPIase) …
Hydrogen gas inhalation ameliorates cardiac remodelling and fibrosis by regulating NLRP3 inflammasome in myocardial infarction rats
C Nie, R Zou, S Pan, Y Gao, H Yang… - Journal of Cellular …, 2021 - Wiley Online Library
It is noteworthy that prolonged cardiac structural changes and excessive fibrosis caused by
myocardial infarction (MI) seriously interfere with the treatment of heart failure in clinical …
myocardial infarction (MI) seriously interfere with the treatment of heart failure in clinical …