Heterogeneity and plasticity of epithelial–mesenchymal transition (EMT) in cancer metastasis: Focusing on partial EMT and regulatory mechanisms
D Li, L Xia, P Huang, Z Wang, Q Guo, C Huang… - Cell …, 2023 - Wiley Online Library
Epithelial–mesenchymal transition (EMT) or mesenchymal–epithelial transition (MET) plays
critical roles in cancer metastasis. Recent studies, especially those based on single‐cell …
critical roles in cancer metastasis. Recent studies, especially those based on single‐cell …
[HTML][HTML] KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition
Lung squamous cell carcinoma (LUSC) represents a major subtype of lung cancer with
limited treatment options. KMT2D is one of the most frequently mutated genes in LUSC (> …
limited treatment options. KMT2D is one of the most frequently mutated genes in LUSC (> …
Pulmonary squamous cell carcinoma and lymphoepithelial carcinoma–morphology, molecular characteristics and differential diagnosis
S Berezowska, M Maillard, M Keyter, B Bisig - Histopathology, 2024 - Wiley Online Library
Squamous cell carcinoma (SCC) comprises one of the major groups of non‐small‐cell
carcinoma of the lung, and is subtyped into keratinising, non‐keratinising and basaloid SCC …
carcinoma of the lung, and is subtyped into keratinising, non‐keratinising and basaloid SCC …
[HTML][HTML] Metabolomic differentiation of benign vs malignant pulmonary nodules with high specificity via high-resolution mass spectrometry analysis of patient sera
Y Yao, X Wang, J Guan, C Xie, H Zhang, J Yang… - Nature …, 2023 - nature.com
Differential diagnosis of pulmonary nodules detected by computed tomography (CT)
remains a challenge in clinical practice. Here, we characterize the global metabolomes of …
remains a challenge in clinical practice. Here, we characterize the global metabolomes of …
[HTML][HTML] USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticity
Lung squamous cell carcinoma (LUSC) is associated with high mortality and limited targeted
therapies. USP13 is one of the most amplified genes in LUSC, yet its role in lung cancer is …
therapies. USP13 is one of the most amplified genes in LUSC, yet its role in lung cancer is …
[HTML][HTML] Expanding Broad Molecular Reflex Testing in Non-Small Cell Lung Cancer to Squamous Histology
M Zacharias, S Konjic, N Kratochwill, G Absenger… - Cancers, 2024 - mdpi.com
Simple Summary Targeted therapies have revolutionized the treatment of patients with non-
small cell lung cancer (NSCLC). Adenocarcinoma, the most common histological subtype of …
small cell lung cancer (NSCLC). Adenocarcinoma, the most common histological subtype of …
Smoking-induced CCNA2 expression promotes lung adenocarcinoma tumorigenesis by boosting AT2/AT2-like cell differentiation
Q He, M Qu, C Xu, L Wu, Y Xu, J Su, H Bao, T Shen… - Cancer Letters, 2024 - Elsevier
Lung adenocarcinoma (LUAD), a type of non-small cell lung cancer (NSCLC), originates
from not only bronchial epithelial cells but also alveolar type 2 (AT2) cells, which could …
from not only bronchial epithelial cells but also alveolar type 2 (AT2) cells, which could …
Successful treatment of immune-related lichenoid dermatitis by Weiling decoction in a patient with non-small cell lung cancer: a case report and review of literature
Y Liu, J Tang, LY Yu, Q Jiang - EXPLORE, 2023 - Elsevier
Abstract Background Immune checkpoint inhibitors (ICIs) have emerged as a revolutionary
therapy in advanced squamous non-small cell lung cancer (sqNSCLC) and ushered a new …
therapy in advanced squamous non-small cell lung cancer (sqNSCLC) and ushered a new …
[HTML][HTML] Systematic analysis of apoptosis-related genes in the prognosis of lung squamous cell carcinoma: a combined single-cell RNA sequencing study
P Zhu, W Yang, B Wang, T Zeng, Z Hu… - Journal of Thoracic …, 2023 - ncbi.nlm.nih.gov
Background Lung squamous cell carcinoma (LUSC) has a poor prognosis and lacks
appropriate diagnostic and treatment strategies. Apoptosis dysregulation is associated with …
appropriate diagnostic and treatment strategies. Apoptosis dysregulation is associated with …
[HTML][HTML] Characterization of stemness features and construction of a stemness subtype classifier to predict survival and treatment responses in lung squamous cell …
J Lai, X Lin, H Zheng, B Xie, D Fu - BMC cancer, 2023 - Springer
Background Cancer stemness has been proven to affect tumorigenesis, metastasis, and
drug resistance in various cancers, including lung squamous cell carcinoma (LUSC). We …
drug resistance in various cancers, including lung squamous cell carcinoma (LUSC). We …