[HTML][HTML] Immunopathology of chronic hepatitis B infection: role of innate and adaptive immune response in disease progression
A Khanam, JV Chua, S Kottilil - International Journal of Molecular …, 2021 - mdpi.com
More than 250 million people are living with chronic hepatitis B despite the availability of
highly effective vaccines and oral antivirals. Although innate and adaptive immune cells play …
highly effective vaccines and oral antivirals. Although innate and adaptive immune cells play …
Hepatitis B surface antigen seroclearance: immune mechanisms, clinical impact, importance for drug development
I Tout, D Loureiro, A Mansouri, V Soumelis, N Boyer… - Journal of …, 2020 - Elsevier
HBsAg seroclearance occurs rarely in the natural history of chronic hepatitis B (CHB)
infection and is associated with improved clinical outcomes. Many factors are associated …
infection and is associated with improved clinical outcomes. Many factors are associated …
[HTML][HTML] Cytokines and chemokines in HBV infection
S Zhong, T Zhang, L Tang, Y Li - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Chronic hepatitis B virus (HBV) infection remains a leading cause of hepatic inflammation
and damage. The pathogenesis of chronic hepatitis B (CHB) infection is predominantly …
and damage. The pathogenesis of chronic hepatitis B (CHB) infection is predominantly …
[HTML][HTML] The role of interleukins in HBV infection: A narrative review
K Dimitriadis, S Katelani, M Pappa… - Journal of Personalized …, 2023 - mdpi.com
Hepatitis B virus (HBV) infection is a worldwide medical issue with significant morbidity and
mortality, as it is the main cause of chronic liver disease and hepatocellular carcinoma …
mortality, as it is the main cause of chronic liver disease and hepatocellular carcinoma …
Association of cytokines with hepatitis B virus and its antigen
M Li, Q Chen, L Zhang, H Lu, F Sun… - Journal of Medical …, 2020 - Wiley Online Library
To investigate the characteristics of cytokines in patients with different HBV infection status
and their correlation with HBV DNA, HBsAg, and HBeAg levels. Peripheral blood samples …
and their correlation with HBV DNA, HBsAg, and HBeAg levels. Peripheral blood samples …
Programmed death 1 expressing CD8+CXCR5+ follicular T cells constitute effector rather than exhaustive phenotype in patients with chronic hepatitis B
A Khanam, LSY Tang, S Kottilil - Hepatology, 2022 - Wiley Online Library
Abstract Background and Aims Classical CD8 T cells are implicated for protective and
pathogenic roles in chronic hepatitis B (CHB) infection. Recently, a subset of CD8 T cells …
pathogenic roles in chronic hepatitis B (CHB) infection. Recently, a subset of CD8 T cells …
[HTML][HTML] Characterization of T cell immunity in chronic hepatitis B virus-infected mothers with postpartum alanine transaminase flare
M Huang, Y Gao, X Yin, X Zhang, Y Hao, J Hu… - BMC Infectious …, 2021 - Springer
Background Postpartum alanine transaminase (ALT) flares occur frequently in chronic
hepatitis B virus (HBV)-infected mothers with antepartum antiviral therapy (AVT). We aimed …
hepatitis B virus (HBV)-infected mothers with antepartum antiviral therapy (AVT). We aimed …
[HTML][HTML] Hepatitis B and circadian rhythm of the liver
The circadian rhythm in humans is determined by the central clock located in the
hypothalamus's suprachiasmatic nucleus, and it synchronizes the peripheral clocks in other …
hypothalamus's suprachiasmatic nucleus, and it synchronizes the peripheral clocks in other …
[HTML][HTML] HBeAg is indispensable for inducing liver sinusoidal endothelial cell activation by hepatitis B virus
X Xie, J Luo, D Zhu, W Zhou, X Yang, X Feng… - Frontiers in Cellular …, 2022 - frontiersin.org
Background and Aims Liver sinusoidal endothelial cells (LSECs) serve as sentinel cells to
detect microbial infection and actively contribute to regulating immune responses for …
detect microbial infection and actively contribute to regulating immune responses for …
[HTML][HTML] Chronic hepatitis B infection is associated with increased molecular degree of inflammatory perturbation in peripheral blood
CL Vinhaes, LAB Cruz, RC Menezes, TA Carmo… - Viruses, 2020 - mdpi.com
Hepatitis B virus (HBV) infection remains a major public health concern. The interaction
between HBV and the host inflammatory response is an important contributing factor driving …
between HBV and the host inflammatory response is an important contributing factor driving …