Therapeutic Potential of Ginsenosides on Bone Metabolism: A Review of Osteoporosis, Periodontal Disease and Osteoarthritis

SY Ko - International Journal of Molecular Sciences, 2024 - mdpi.com
Ginsenosides, bioactive compounds from the genus Panax, have potential therapeutic
effects on diverse ailments, including diabetes. Emerging evidence suggests their …

cGAS-STING pathway in pathogenesis and treatment of osteoarthritis and rheumatoid arthritis

XC Yang, LL Zhao, YQ Pang - Frontiers in Immunology, 2024 - frontiersin.org
Osteoarthritis (OA) and Rheumatoid Arthritis (RA) are significant health concerns with
notable prevalence and economic impact. RA, affecting 0.5% to 1.0% of the global …

Total flavonoids of rhizoma drynariae treat osteoarthritis by inhibiting arachidonic acid metabolites through AMPK/NFκB pathway

GY Chen, XY Liu, XE Yan, XB Yu, Y Liu… - Journal of …, 2023 - Taylor & Francis
Objective Previous clinical studies have found that total flavonoids of Rhizoma Drynariae
(TFRD) have a good therapeutic effect on osteoarthritis (OA), but its therapeutic mechanism …

[HTML][HTML] Pain after combat injury in male UK military personnel deployed to Afghanistan

J Vollert, A Kumar, EC Coady, P Cullinan… - British journal of …, 2024 - Elsevier
Background Chronic pain after injury poses a serious health burden. As a result of advances
in medical technology, ever more military personnel survive severe combat injuries, but long …

[HTML][HTML] Molecular mechanisms and potential applications of chondroitin sulphate in managing post-traumatic osteoarthritis

I Golovach, D Rekalov, Y Akimov, H Kostenko… - …, 2023 - ncbi.nlm.nih.gov
Abstract Post-traumatic osteoarthritis (PTOA), a disorder of the synovium, subchondral bone,
and cartilage that affects the entire joint, constitutes approximately 12% of all cases of …

[PDF][PDF] Research progress of procyanidins in repairing cartilage injury after anterior cruciate ligament tear

H Chen, J Li, S Li, X Wang, G Xu, M Li, G Li - Heliyon, 2024 - cell.com
Anterior cruciate ligament (ACL) tear is a common sports-related injury, and cartilage injury
always emerges as a serious complication following ACL tear, significantly impacting the …

Effects of dexamethasone and IGF-1 on post-traumatic osteoarthritis-like catabolic changes in a human cartilage-bone-synovium microphysiological system in space …

G Dwivedi, L Flaman, B Alaybeyoglu… - Frontiers in Space …, 2024 - frontiersin.org
Post-traumatic Osteoarthritis (PTOA) results from traumatic joint injuries (such as an ACL
rupture). Mechanical impact and an immediate synovial inflammatory response can result in …

A Reproducible Cartilage Impact Model to Generate Post-Traumatic Osteoarthritis in the Rabbit

J Dilley, H Noori-Dokht, A Seetharam, M Bello… - JoVE (Journal of …, 2023 - jove.com
Post-traumatic osteoarthritis (PTOA) is responsible for 12% of all osteoarthritis cases in the
United States. PTOA can be initiated by a single traumatic event, such as a high-impact load …

[HTML][HTML] Inflammatory mechanisms in post-traumatic osteoarthritis: a role for CaMKK2

KC Riggs, U Sankar - Immunometabolism, 2023 - journals.lww.com
Post-traumatic osteoarthritis (PTOA) is a multifactorial disease of the cartilage, synovium,
and subchondral bone resulting from direct joint trauma and altered joint mechanics after …

[HTML][HTML] A Comprehensive Review of Total Hip Arthroplasty Outcomes in Post-traumatic Hip Arthritis: Insights and Perspectives

A Choudhary, G Pisulkar, S Taywade, AA Awasthi… - Cureus, 2024 - ncbi.nlm.nih.gov
Post-traumatic hip arthritis presents a challenging condition characterized by degenerative
changes in the hip joint following traumatic injury. Total hip arthroplasty (THA) is a …