[HTML][HTML] Network pharmacology and experimental verification reveal the mechanism of safranal against glioblastoma (GBM)
X Yang, D Lu, Y Sun, T Wei, D Man, A Chen… - Frontiers in …, 2023 - frontiersin.org
Introduction Safranal is an active component of the traditional Tibetan medicine (TTM)
saffron, which has potential anticancer activity. Methods and results Here, we studied the …
saffron, which has potential anticancer activity. Methods and results Here, we studied the …
Crocetin and related oxygen diffusion‐enhancing compounds: Review of chemical synthesis, pharmacology, clinical development, and novel therapeutic applications
The current pandemic forced us to introspect and revisit our armamentarium of medicinal
agents which could be life‐saving in emergency situations. Oxygen diffusion‐enhancing …
agents which could be life‐saving in emergency situations. Oxygen diffusion‐enhancing …
Crocin restores the balance of Th1/Th2 immune cell response in ConA-treated human lymphocytes
Background Following antigen stimulation, naive CD4+ T cells differentiate into different T
helper (Th) subsets characterized by lineage-specific transcriptional factors and cytokines …
helper (Th) subsets characterized by lineage-specific transcriptional factors and cytokines …
Identification of the therapeutic mechanism of the saffron crocus on glioma through network pharmacology and bioinformatics analysis
X Yang, D Man, P Zhao, X Li - Medical Oncology, 2023 - Springer
Saffron crocus is a herbal medicine of traditional Tibetan medicine (TTM). Saffron extract has
been indicated to inhibit tumor cell growth and promote tumor cell apoptosis in a variety of …
been indicated to inhibit tumor cell growth and promote tumor cell apoptosis in a variety of …
[HTML][HTML] Crocin induces autophagic cell death and inhibits cell invasion of cervical cancer SiHa cells through activation of PI3K/AKT
J Zhang, S Yang, K Wang, Y Huang… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Cervical cancer is a prevalent tumor mainly induced by Human Papilloma Virus
(HPV). Autophagy was inactivated with HPV to promote cancer progression. Here we …
(HPV). Autophagy was inactivated with HPV to promote cancer progression. Here we …
[HTML][HTML] Bio-guided bioactive profiling and HPLC-DAD fingerprinting of Ukrainian saffron (Crocus sativus stigmas): moving from correlation toward causation
Background Saffron or stigmas of Crocus sativus L. is one of the most valuable food
products with interesting health-promoting properties. C. sativus has been widely used as a …
products with interesting health-promoting properties. C. sativus has been widely used as a …
Medicinal properties of saffron with special reference to cancer—A review of preclinical studies
Saffron (Crocus sativus) is a perennial herb, mainly grown in Mediterranean Europe,
western Asia, and Kashmir region of India. The dried stigmas of the C. sativus have been …
western Asia, and Kashmir region of India. The dried stigmas of the C. sativus have been …
[HTML][HTML] Crocin promotes apoptosis in human EBV-transformed B-lymphocyte via intrinsic pathway
Background As a major carotenoid in saffron, crocin demonstrates potent anti-cancer
impacts. However, its anti-lymphoma effects remain vague, especially in the human EBV …
impacts. However, its anti-lymphoma effects remain vague, especially in the human EBV …
Pediatric acute lymphoblastic leukemia management using multitargeting bioactive natural compounds: A systematic and critical review
F Nabizadeh, S Momtaz, M Ghanbari-Movahed… - Pharmacological …, 2022 - Elsevier
Pediatric acute lymphoblastic leukemia (pALL), a malignancy of the lymphoid line of blood
cells, accounts for a large percentage of all childhood leukemia cases. Although the 5-year …
cells, accounts for a large percentage of all childhood leukemia cases. Although the 5-year …
[HTML][HTML] Revealing the dynamics of saffron growth: Optimizing corm size and planting depth for increased yield synergies
Saffron, the" golden spice" derived from Crocus sativus L., is renowned for its richness in
secondary metabolites such as crocin and safranal, contributing to its unique properties …
secondary metabolites such as crocin and safranal, contributing to its unique properties …