Advancements in nanoparticle-based treatment approaches for skin cancer therapy
Skin cancer has emerged as the fifth most commonly reported cancer in the world, causing a
burden on global health and the economy. The enormously rising environmental changes …
burden on global health and the economy. The enormously rising environmental changes …
RNAi-based therapeutics and tumor targeted delivery in cancer
Over the past decade, non-coding RNA-based therapeutics have proven as a great potential
for the development of targeted therapies for cancer and other diseases. The discovery of …
for the development of targeted therapies for cancer and other diseases. The discovery of …
Huntington disease: new insights into molecular pathogenesis and therapeutic opportunities
Huntington disease (HD) is a neurodegenerative disease caused by CAG repeat expansion
in the huntingtin gene (HTT) and involves a complex web of pathogenic mechanisms …
in the huntingtin gene (HTT) and involves a complex web of pathogenic mechanisms …
Nucleic acid delivery for therapeutic applications
Recent medical advances have exploited the ability to address a given disease at the
underlying level of transcription and translation. These treatment paradigms utilize nucleic …
underlying level of transcription and translation. These treatment paradigms utilize nucleic …
Polymeric delivery of therapeutic nucleic acids
R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Transfection types, methods and strategies: a technical review
Transfection is a modern and powerful method used to insert foreign nucleic acids into
eukaryotic cells. The ability to modify host cells' genetic content enables the broad …
eukaryotic cells. The ability to modify host cells' genetic content enables the broad …
RNA therapeutics: updates and future potential
C Zhang, B Zhang - Science China Life Sciences, 2023 - Springer
Recent advancements in the production, modification, and cellular delivery of RNA
molecules facilitated the expansion of RNA-based therapeutics. The increasing …
molecules facilitated the expansion of RNA-based therapeutics. The increasing …
Nanoparticle‐mediated double‐stranded RNA delivery system: A promising approach for sustainable pest management
S Yan, BY Ren, J Shen - Insect Science, 2021 - Wiley Online Library
RNA interference (RNAi) targeting lethal genes in insects has great potential for sustainable
crop protection. Compared with traditional double‐stranded (ds) RNA delivery systems …
crop protection. Compared with traditional double‐stranded (ds) RNA delivery systems …
Strategies for the development and approval of COVID-19 vaccines and therapeutics in the post-pandemic period
D Ao, X He, J Liu, L Xu - Signal Transduction and Targeted Therapy, 2023 - nature.com
The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted
in significant casualties and put immense strain on public health systems worldwide, leading …
in significant casualties and put immense strain on public health systems worldwide, leading …
Artificial nanovesicles for dsRNA delivery in spray‐induced gene silencing for crop protection
L Qiao, J Niño‐Sánchez, R Hamby… - Plant Biotechnology …, 2023 - Wiley Online Library
Spray‐induced gene silencing (SIGS) is an innovative and eco‐friendly technology where
topical application of pathogen gene‐targeting RNAs to plant material can enable disease …
topical application of pathogen gene‐targeting RNAs to plant material can enable disease …